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A New Fluorescent Probe for Hydrogen Sulfide Detection in So-Lution and Living Cells
Version 1
: Received: 4 July 2023 / Approved: 4 July 2023 / Online: 4 July 2023 (11:45:21 CEST)
A peer-reviewed article of this Preprint also exists.
Feng, W.; Xiao, Q.; Wang, L.; Yang, Y. A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells. Molecules 2023, 28, 6195. Feng, W.; Xiao, Q.; Wang, L.; Yang, Y. A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells. Molecules 2023, 28, 6195.
Abstract
Since Hydrogen Sulfide (H2S) was recognized as a gas transmitter, its detection and quantifica-tion have become a hot research topic among chemists and biologists. In this area. fluorescent probes have shown great advantages: fast and strong responds, low detection limit and easy ma-nipulation. Here we developed a new fluorescent probe that detected H2S selectively among various bioactive and inorganic salts. This probe was based on the core structure of fluorescein and reacted with H2S through azide-reduction. Great linearity was achieved correlating fluores-cence intensity and H2S concentrations in solution. The detection of H2S in cancer cells was also achieved.
Keywords
Hydrogen Sulfide; Fluorescent Probe; H2S Selective Detection; H2S Quantification; Az-ide-Reduction
Subject
Chemistry and Materials Science, Analytical Chemistry
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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