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Version 1
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Asthma Phenotypes in the Era of Personalized Medicine
Version 1
: Received: 22 July 2023 / Approved: 24 July 2023 / Online: 24 July 2023 (11:01:29 CEST)
A peer-reviewed article of this Preprint also exists.
Gonzalez-Uribe, V.; Romero-Tapia, S.J.; Castro-Rodriguez, J.A. Asthma Phenotypes in the Era of Personalized Medicine. J. Clin. Med. 2023, 12, 6207. Gonzalez-Uribe, V.; Romero-Tapia, S.J.; Castro-Rodriguez, J.A. Asthma Phenotypes in the Era of Personalized Medicine. J. Clin. Med. 2023, 12, 6207.
Abstract
Asthma is a prevalent disease that around 300 million worldwide, resulting in substantial morbidity, mortality, and economic burden on a global scale. New clinical and laboratory research has shed light on the immunology causing asthma. Asthma is now recognized as a heterogeneous disease. A personalized medicine is based on the classification of asthma by endotype by linking observable characteristics to immunological mechanisms. Identifying endotype mechanisms is essential for better characterizing patients and personalizing therapeutic approaches with novel biological agents that target specific immune pathways. This article provides a summary of the major immunological mechanisms involved in the pathogenesis and emergence of the disease's phenotypic features, as well as the individualized treatment for severe asthma subtypes
Keywords
asthma; precision medicine; phenotypes; endotypes; pathogenetic mechanism
Subject
Medicine and Pharmacology, Pulmonary and Respiratory Medicine
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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