Review
Version 1
Preserved in Portico This version is not peer-reviewed
Phytochemistry and biological activities of Cissus trifoliata against carcinomas
Version 1
: Received: 30 December 2023 / Approved: 3 January 2024 / Online: 3 January 2024 (05:35:44 CET)
How to cite: Méndez-López, L. F. Phytochemistry and biological activities of Cissus trifoliata against carcinomas. Preprints 2024, 2024010147. https://doi.org/10.20944/preprints202401.0147.v1 Méndez-López, L. F. Phytochemistry and biological activities of Cissus trifoliata against carcinomas. Preprints 2024, 2024010147. https://doi.org/10.20944/preprints202401.0147.v1
Abstract
There is an urgent need to develop new therapies for cancer treatment due to high rates of resistance and tumor relapse. Moreover, chemotherapy and radiation weaken the immune system and leave patients susceptible to sudden death from infections and organ failure since antineoplastic drugs lack specificity. Hence, scientists worldwide continue the search for natural alternatives with anticancer activities and fewer side effects. In this regard, traditional medicine offers strategies for preventing and treating numerous diseases and nowadays scientific studies worldwide highlight some of the mechanisms underlying their potential as an effective alternative for the management of cancer. In Mexico, Mayan healers have been prescribed mainly medicinal plants for more than 2,000 years. Furthermore, their ethnomedical knowledge has led to drug discovery or the development of herbal remedies. Medicinal plants from the genus of Cissus remain an important element of all indigenous medical systems in Mexico including the Mayan tribes in Yucatan, particularly for the management of gastrointestinal illnesses, sores, cutaneous diseases, and tumors. In this review, we present the reported bioactivities against cancer cells of the extract and compounds from the species of Cissus with a particular focus on recent studies on the phytochemistry of C. trifoliata which is widely distributed in Mexican territory and used for tumor management in traditional medicine.
Keywords
Cissus sp., Phytochemicals, Apoptosis, Proliferation, EMT, Anticancer
Subject
Medicine and Pharmacology, Pharmacy
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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