Article
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Preserved in Portico This version is not peer-reviewed
Test-Retest Reproducibility of Reduced Field of View Density-Weighted CRT MRSI at 3T
Version 1
: Received: 20 February 2024 / Approved: 21 February 2024 / Online: 21 February 2024 (14:59:03 CET)
A peer-reviewed article of this Preprint also exists.
Farley, N.; Susnjar, A.; Chiew, M.; Emir, U.E. Test–Retest Reproducibility of Reduced-Field-of-View Density-Weighted CRT MRSI at 3T. Tomography 2024, 10, 493-503. Farley, N.; Susnjar, A.; Chiew, M.; Emir, U.E. Test–Retest Reproducibility of Reduced-Field-of-View Density-Weighted CRT MRSI at 3T. Tomography 2024, 10, 493-503.
Abstract
Quantifying an imaging modality’s ability to reproduce results is important for establishing its utility. In Magnetic Resonance Spectroscopic Imaging (MRSI), new acquisition protocols are regularly introduced, which improve upon their precursors with respect to signal-to-noise ratio (SNR), total acquisition duration, and nominal voxel resolution. This study has quantified the within-subject and between-subject reproducibility of one such new protocol (reduced-Field-of-View-Density-Weighted-Concentric-Ring-Trajectory (rFOV-DW-CRT) MRSI) by calculating the Coefficient of Variance of data acquired from a test-retest experiment. The Posterior Cingulate Cortex (PCC) and the Right Superior Corona Radiata (SCR) were selected as the Regions of Interest (ROIs) for Grey Matter (GM) and White Matter (WM), respectively. CVs for between-subject and within-subject are consistently around or below 15% for Glx, tCho, and Myo-Ins and below 5% for tNAA and tCr.
Keywords
Non-Cartesian; Nuclear; Magnetic; Resonance; Spectroscopy; Imaging; Test-Retest; Reproducibility
Subject
Biology and Life Sciences, Neuroscience and Neurology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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