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TAFRO Syndrome on 18F-FDG-PET/CT: An Appealing Diagnostic Tool
Version 1
: Received: 22 April 2024 / Approved: 23 April 2024 / Online: 23 April 2024 (11:58:18 CEST)
A peer-reviewed article of this Preprint also exists.
Jaafari, A.; Taheri, N.; Mansour, S.; El Bouhali, S.-E.; Attou, R. TAFRO Syndrome on 18F-FDG-PET/CT: An Appealing Diagnostic Tool. Diagnostics 2024, 14, 1025. Jaafari, A.; Taheri, N.; Mansour, S.; El Bouhali, S.-E.; Attou, R. TAFRO Syndrome on 18F-FDG-PET/CT: An Appealing Diagnostic Tool. Diagnostics 2024, 14, 1025.
Abstract
TAFRO syndrome (TS) is a rare variant of idiopathic multicentric Castleman's disease (iMCD) characterized by a confluence of symptoms: thrombocytopenia (T), anasarca (A), fever (F), reticulin myelofibrosis (R), and organomegaly (O). First described in Japan in 2010, the pathogenesis of the disease remains unclear. Due to its heterogeneous presentation and potential life-threatening delays in diagnosis, precise diagnosis is essential. According to the literature, no specific imaging modality has been recommended for the work-up of patients with suspected TS. Here, we report a case of TS and its management using 18F-FDG-PET/CT imaging as an attractive complementary diagnostic tool.
Keywords
TAFRO syndrome; multicentric Castleman disease; iMCD; 18F-FDG-PET/CT
Subject
Medicine and Pharmacology, Internal Medicine
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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