Version 1
: Received: 13 May 2024 / Approved: 13 May 2024 / Online: 14 May 2024 (11:21:01 CEST)
How to cite:
Maeso Mendez, S.; Gago Martin, R.; Jauregui Benito, E.; Costa Serra, L.; Gainzarain Serna, A.; Prigent Diaz, A.; Sola Sarabia, C.; Ogueta Lana, M.; Diez Lopez, I. Influence Use of the Bacillus Calmette- Guérin Vaccine on the Incidence Type 1 Diabetes Mellitus Onset in a Child and Adolescent Population. Preprints2024, 2024050906. https://doi.org/10.20944/preprints202405.0906.v1
Maeso Mendez, S.; Gago Martin, R.; Jauregui Benito, E.; Costa Serra, L.; Gainzarain Serna, A.; Prigent Diaz, A.; Sola Sarabia, C.; Ogueta Lana, M.; Diez Lopez, I. Influence Use of the Bacillus Calmette- Guérin Vaccine on the Incidence Type 1 Diabetes Mellitus Onset in a Child and Adolescent Population. Preprints 2024, 2024050906. https://doi.org/10.20944/preprints202405.0906.v1
Maeso Mendez, S.; Gago Martin, R.; Jauregui Benito, E.; Costa Serra, L.; Gainzarain Serna, A.; Prigent Diaz, A.; Sola Sarabia, C.; Ogueta Lana, M.; Diez Lopez, I. Influence Use of the Bacillus Calmette- Guérin Vaccine on the Incidence Type 1 Diabetes Mellitus Onset in a Child and Adolescent Population. Preprints2024, 2024050906. https://doi.org/10.20944/preprints202405.0906.v1
APA Style
Maeso Mendez, S., Gago Martin, R., Jauregui Benito, E., Costa Serra, L., Gainzarain Serna, A., Prigent Diaz, A., Sola Sarabia, C., Ogueta Lana, M., & Diez Lopez, I. (2024). Influence Use of the Bacillus Calmette- Guérin Vaccine on the Incidence Type 1 Diabetes Mellitus Onset in a Child and Adolescent Population. Preprints. https://doi.org/10.20944/preprints202405.0906.v1
Chicago/Turabian Style
Maeso Mendez, S., Mikel Ogueta Lana and Ignacio Diez Lopez. 2024 "Influence Use of the Bacillus Calmette- Guérin Vaccine on the Incidence Type 1 Diabetes Mellitus Onset in a Child and Adolescent Population" Preprints. https://doi.org/10.20944/preprints202405.0906.v1
Abstract
Introduction: Type 1 diabetes mellitus is a chronic disease of autoimmune etiology that is highly prevalent in childhood. In the last decade, the possibility of using the Bacillus Calmette-Guérin vaccine for the treatment of this disease has been studied thanks to its immunomodulatory action .
Objectives: The objective of this work is to carry out a systematic review of the available scientific evidence on the relationship between the tuberculosis vaccine and the treatment of diabetes in childhood. Secondarily, the aim is to study the incidence of Type 1 Diabetes Mellitus in a cohort of children from the Basque Country according to whether or not they have received the vaccine.
Methods: An exhaustive bibliographic search has been carried out on the evidence available to date. For the epidemiological study in Euskadi, a comparison of accumulated incidences between vaccinated and unvaccinated population groups was made.
Results: According to the literature analyzed, There is more and more evidence about the possible use of the tuberculosis vaccine in Type 1 Diabetes Mellitus. The results of our study were not conclusive, but we believe that it is necessary to continue with long-term studies to eliminate biases.
Conclusions: The Bacillus Calmette-Guérin vaccine could be used for the treatment of autoimmune, allergic, infectious or oncological processes, although more studies are still necessary in this regard.
Keywords
BCG vaccine; Diabetes Mellitus type 1; Mycobacterium tuberculosis.
Subject
Biology and Life Sciences, Endocrinology and Metabolism
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
