Article
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Preserved in Portico This version is not peer-reviewed
Innovative Sensor Approach to Follow Campylobacter jejuni Development
Version 1
: Received: 31 October 2018 / Approved: 2 November 2018 / Online: 2 November 2018 (03:28:13 CET)
A peer-reviewed article of this Preprint also exists.
Núñez-Carmona, E.; Abbatangelo, M.; Sberveglieri, V. Innovative Sensor Approach to Follow Campylobacter jejuni Development. Biosensors 2019, 9, 8. Núñez-Carmona, E.; Abbatangelo, M.; Sberveglieri, V. Innovative Sensor Approach to Follow Campylobacter jejuni Development. Biosensors 2019, 9, 8.
Abstract
Campylobacter infection affects more than 200,000 people every year in Europe and in the last four years trend shows an increase of campylobacteriosis. Main vehicle for transmission of the bacterium is contaminated food like meat, milk, fruit and vegetables. In this study, the aim was to find characteristic VOCs of C. jejuni in order to detect its presence with an array of MOX gas sensors. Using a starting concentration of 103 CFU/mL, VOCs were analyzed using GC-MS with SPME technique at the initial time (T0) and after 20 hours (T20). It has been found that Campylobacter sample at T20 is characterized by a higher number of alcohol compounds that the one at T0 and this is due to sugar fermentation. Sensors results showed the ability of the system to follow bacteria curve growth from T0 to T20 using PCA. In particular, this results in a decrease of ΔR/R0 value over time. For this reason, MOX sensors are a promising technology for the development of a rapid and sensitive system for C. jejuni.
Keywords
campylobacter jejuni; VOCs; GC-MS SPME; nanowire sensors; PCA
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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