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Regeneration of the Periodontal Apparatus in Aggressive Periodontitis Patients
Version 1
: Received: 18 January 2019 / Approved: 21 January 2019 / Online: 21 January 2019 (08:58:50 CET)
A peer-reviewed article of this Preprint also exists.
Artzi, Z.; Sudri, S.; Platner, O.; Kozlovsky, A. Regeneration of the Periodontal Apparatus in Aggressive Periodontitis Patients. Dent. J. 2019, 7, 29. Artzi, Z.; Sudri, S.; Platner, O.; Kozlovsky, A. Regeneration of the Periodontal Apparatus in Aggressive Periodontitis Patients. Dent. J. 2019, 7, 29.
Abstract
The aim of this article is to evaluate and compare, retrospectively, the efficacy of two regenerative periodontal procedures in patients suffering from aggressive periodontitis (AgP). Twenty-eight patients were diagnosed with AgP, suffering from multiple intra-bony defects (IBD); that were treated by one of two regenerative modalities of periodontal therapy randomly assigned to each patient: a. guided tissue regeneration (GTR) or b. an application of enamel matrix derivatives (EMD) combined with DBX. The monitoring of the treated sites included recordings of probing depth (PD), clinical attachment level (CAL), and gingival recession. Pre-treatment and follow-up (up to 10 years from the surgery) recordings were analyzed statistically within and between groups. A significant reduction was shown at time on PD and CAL values, however, not between subject groups. CAL values decreased in all sites. At EMD group (44 sites) CAL gain was 1.92 mm (±1.68) from pre-treatment to follow-up (p<0.001) and at the GTR group (12 sites) CAL gain of 2.27 (±1.82) mm. In conclusion, 1-10 years observations have shown that surgical treatment of AgP patients by either GTR or by application of EMD/DBX results in similar successful clinical results.
Keywords
periodontal regeneration; aggressive periodontitis; deproteinized bovine bone; enamel matrix derivatives (Emdogain®); guided tissue regeneration (GTR)
Subject
Medicine and Pharmacology, Dentistry and Oral Surgery
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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