Article
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Studying a Light Sensor with Light: Multiphoton Imaging in the Retina
Version 1
: Received: 25 March 2019 / Approved: 26 March 2019 / Online: 26 March 2019 (14:01:49 CET)
How to cite: Euler, T.; Franke, K.; Baden, T. Studying a Light Sensor with Light: Multiphoton Imaging in the Retina. Preprints 2019, 2019030244. https://doi.org/10.20944/preprints201903.0244.v1 Euler, T.; Franke, K.; Baden, T. Studying a Light Sensor with Light: Multiphoton Imaging in the Retina. Preprints 2019, 2019030244. https://doi.org/10.20944/preprints201903.0244.v1
Abstract
Two-photon imaging of light stimulus-evoked neuronal activity has been used to study all neuron classes in the vertebrate retina, from the photoreceptors to the retinal ganglion cells. Clearly, the ability to study retinal circuits down to the level of single synapses or zoomed out at the level of complete populations of neurons, has been a major asset in our understanding of this beautiful circuit. In this chapter, we discuss the possibilities and pitfalls of using an all-optical approach in this highly light-sensitive part of the brain.
Keywords
vertebrate retina, mouse, zebrafish, two-photon microscopy, biosensor, activity probes, visual stimulus-evoked activity, laser-evoked retinal activity
Subject
Biology and Life Sciences, Neuroscience and Neurology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Commenter: Shinya Sato
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