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From Minor Mutant to Dominance, the Evolution of SARS-CoV-2 Variants
Version 1
: Received: 5 July 2022 / Approved: 6 July 2022 / Online: 6 July 2022 (15:27:32 CEST)
How to cite: Caspari, T. From Minor Mutant to Dominance, the Evolution of SARS-CoV-2 Variants. Preprints 2022, 2022070100. https://doi.org/10.20944/preprints202207.0100.v1 Caspari, T. From Minor Mutant to Dominance, the Evolution of SARS-CoV-2 Variants. Preprints 2022, 2022070100. https://doi.org/10.20944/preprints202207.0100.v1
Abstract
The successive waves of the Covid-19 pandemic are driven by SARS-CoV-2 variants that reached critical detection levels in different parts of the world. But how evolved the Wuhan virus since its detection in December 2019 into the Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2) and Omicron (B.1.1.529) variants of concern? This is a story of mice and men, of up to 1,000,000 infected cells in one person, where each cell produces between 105 and 106 viral RNAs, of immune-compromised patients, the digestive tract and viral recombination.
Keywords
omicron; alpha; delta; deltacron; recombination; RNA editing; intra-host variants; tropisms; ox-idative damage; Wuhan
Subject
Biology and Life Sciences, Virology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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