Concept Paper
Version 1
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Diffuse Optical Tomography: Theoretical Basis, Advantages, and Applications
Version 1
: Received: 18 December 2022 / Approved: 21 December 2022 / Online: 21 December 2022 (02:21:42 CET)
How to cite: Peirson, C. Diffuse Optical Tomography: Theoretical Basis, Advantages, and Applications. Preprints 2022, 2022120373. https://doi.org/10.20944/preprints202212.0373.v1 Peirson, C. Diffuse Optical Tomography: Theoretical Basis, Advantages, and Applications. Preprints 2022, 2022120373. https://doi.org/10.20944/preprints202212.0373.v1
Abstract
Diffuse optical tomography (DOT) is an optical medical imaging method that can assess the structural properties of tissues and their functional characteristics, such as hemoglobin concentration, water content, as well as lipid concentration, via three-dimensional image reconstruction. This paper presents the theoretical basis and working principle of diffuse optical tomography. The paper explains how the optical properties of tissue can be imaged by photon migration techniques based on diffusion theory. The author presents the reasoning for near-infrared (NIR) imaging as the most effective technique in terms of quantitative recovery of spectroscopic optical parameters. This work also listed various advantages, applications, and challenges of DOT. The paper also briefly discusses current progress in near-infrared medical imaging and its future direction.
Keywords
Diffuse Optical Tomography, Near-infrared, Inverse problem, Spectroscopy, Medical Imaging, fNIRS, Tissue
Subject
Physical Sciences, Applied Physics
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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