Case Report
Version 1
Preserved in Portico This version is not peer-reviewed
B-Cell Lymphoma of the Middle Ear in a Cat that Responded Well to Multidrug Chemotherapy
Version 1
: Received: 17 August 2023 / Approved: 18 August 2023 / Online: 18 August 2023 (11:25:31 CEST)
A peer-reviewed article of this Preprint also exists.
Takahashi, T.; Nagata, H.; Kondo, H. B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat. Vet. Sci. 2023, 10, 585. Takahashi, T.; Nagata, H.; Kondo, H. B-Cell Lymphoma of the Middle Ear Treated with Multidrug Chemotherapy in a Cat. Vet. Sci. 2023, 10, 585.
Abstract
Primary lymphoma of the middle ear is rare in cats, and little information has been accumulated on the treatment and course. An 11-year-old spayed female mixed-breed cat was brought to our hospital with facial nerve paralysis, which had been stable using prednisolone for 3 months. She was diagnosed with B-cell lymphoma of the right middle ear after otoscopic sampling, which showed evidence of filling of bilateral tympanic bullae on computed tomography. Hepatic metastasis was suspected and she was treated with multidrug chemotherapy, resulting in clinical remission. On day 176, magnetic resonance imaging and computed tomography was performed as a checkup, revealing tumor invasion into the nasopharyngeal region and recurrence of hepatic lesions without any brain abnormality. Nasal congestion then worsened and the patient died on day 228 after presenting with generalized seizures. Clinicians should be aware of the possibility of invasion to surrounding tissues and hepatic metastasis in cases of feline primary middle ear lymphoma.
Keywords
facial nerve; hypoglossal nerve; multidrug resistance; nasopharyngeal polyp; otitis media; prednisolone
Subject
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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