Case Report
Version 1
Preserved in Portico This version is not peer-reviewed
Serious and Progressive Neuropathy Presumably Post Shingrix Vaccination
Version 1
: Received: 8 December 2023 / Approved: 11 December 2023 / Online: 11 December 2023 (10:07:53 CET)
A peer-reviewed article of this Preprint also exists.
Wons, M.J.; Vaghela, A.; Khalid, A.; Brooks, B.D. Serious and Progressive Neuropathy Presumably Post-Shingrix Vaccination. Reports 2024, 7, 5. Wons, M.J.; Vaghela, A.; Khalid, A.; Brooks, B.D. Serious and Progressive Neuropathy Presumably Post-Shingrix Vaccination. Reports 2024, 7, 5.
Abstract
We present a case of serious and progressive neuropathy shortly following administration of the herpes zoster subunit (HZ/su) vaccine. The progressive neuropathy occurred a week following the vaccination and progressed until discharge 16 days post admittance. Mild patient’s symptoms persist. The development of neuropathy following HZ/su is exceedingly rare, with an attributable risk of 3 cases per million vaccines administered. A black box warning was issued for this indication, although diagnosis and treatment were not confirmed for this patient. Reporting cases like this is crucial for a comprehensive understanding of vaccine risks and to characterize the underlying etiology of these serious adverse events.
Keywords
shingrix; neuropathy; vaccine; varicella
Subject
Medicine and Pharmacology, Medicine and Pharmacology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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