Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Nutritional Factors and Survival in a Cohort of Patients with Oral Cancer

Version 1 : Received: 2 May 2024 / Approved: 4 May 2024 / Online: 6 May 2024 (08:46:28 CEST)

How to cite: Buscemi, P.; Randazzo, C.; Buscemi, C.; Barile, A. M.; Finamore, E.; Caruso, R.; Colombrita, P.; Lombardo, M.; Cangemi, S.; Zucchi, G.; Cordova, A.; Lo Casto, A.; Buscemi, S. Nutritional Factors and Survival in a Cohort of Patients with Oral Cancer. Preprints 2024, 2024050202. https://doi.org/10.20944/preprints202405.0202.v1 Buscemi, P.; Randazzo, C.; Buscemi, C.; Barile, A. M.; Finamore, E.; Caruso, R.; Colombrita, P.; Lombardo, M.; Cangemi, S.; Zucchi, G.; Cordova, A.; Lo Casto, A.; Buscemi, S. Nutritional Factors and Survival in a Cohort of Patients with Oral Cancer. Preprints 2024, 2024050202. https://doi.org/10.20944/preprints202405.0202.v1

Abstract

Background: Malnutrition commonly affects patients with oral squamous cell carcinoma (OSCC), which contributes to worsening prognosis. Moreover, specific strategies for diagnosing and managing malnutrition in OSCC are lacking. Methods: This retrospective study included 52 consecutive patients with OSCC who underwent surgery at the University Hospital of Palermo (I) from Jan 2020 to May 2023. In-hospital nutritional support was provided by a dedicated team. The patients were compared with a historical control group of 11 patients. The nutritional treatment consisted of standard oral (ON) or artificial nutrition (AN). Traditional measurements, including bioimpedance-derived body composition and volumetric reconstruction of the posterior paraspinal muscles at the C3 level based on magnetic resonance imaging (MRI-C3), were obtained in 16 patients to investigate sarcopenia. Results: The patients were categorized according to TNM stage: groups A (TNM stages I-III) and B (IVa-IVc). The prevalence of group A patients was 59.6% in the case group and 90.9% in the control group (P

Keywords

Oral cancer; malnutrition; artificial nutrition; bioimpedance analysis

Subject

Medicine and Pharmacology, Dietetics and Nutrition

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