Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Investigation of Systemic Immune Inflammation (SII) Index as an Indicator of Morbidity and Mortality in Type 2 Diabetic Retinopathy Patients in a 4-Year Follow-up Period

Version 1 : Received: 4 May 2024 / Approved: 6 May 2024 / Online: 6 May 2024 (04:49:25 CEST)

A peer-reviewed article of this Preprint also exists.

Tabakoglu, N.T.; Celik, M. Investigation of the Systemic Immune Inflammation (SII) Index as an Indicator of Morbidity and Mortality in Type 2 Diabetic Retinopathy Patients in a 4-Year Follow-Up Period. Medicina 2024, 60, 855. Tabakoglu, N.T.; Celik, M. Investigation of the Systemic Immune Inflammation (SII) Index as an Indicator of Morbidity and Mortality in Type 2 Diabetic Retinopathy Patients in a 4-Year Follow-Up Period. Medicina 2024, 60, 855.

Abstract

Background and Objectives: To investigate the relationship between the SII index and the micro-macro complications and death that develop in the first year and the following 3 years, following the calculation of the index in type 2 diabetic retinopathy patients. Materials and Methods: This study was performed retrospectively with 523 type 2 diabetic retinopathy patients admitted to the endocrinology outpatient clinic of our hospital between January 2019 and December 2019. The demographic, and clinical characteristics of the patients were evaluated using descriptive statistics. Shapiro-Wilk test was used for the normal distribution of quantitative data; Mann-Whitney U, Mc Nemar Chi-square, and Cochran's Q tests were used to analyze SII values between groups and complication rates by years; sensitivity and specificity were determined by ROC analysis and considered statistically significant with a significance level of P

Keywords

Systemic immune inflammation; diabetic retinopathy; type 2 diabetes mellitus; microvascular complications; macrovascular complications

Subject

Medicine and Pharmacology, Endocrinology and Metabolism

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