Version 1
: Received: 8 May 2024 / Approved: 9 May 2024 / Online: 10 May 2024 (09:11:41 CEST)
How to cite:
Nuryandani, E.; Novitasari, E.; Abdurrahman, M. F.; Habibi, N.; Sefrienda, A. R.; Kurnianto, D.; Jasmadi, J.; Andriana, Y. Chemometric Analysis of GC-MS Chemical Profiles and Biological Activities of Three Citrus Essential Oils in Indonesia. Preprints2024, 2024050629. https://doi.org/10.20944/preprints202405.0629.v1
Nuryandani, E.; Novitasari, E.; Abdurrahman, M. F.; Habibi, N.; Sefrienda, A. R.; Kurnianto, D.; Jasmadi, J.; Andriana, Y. Chemometric Analysis of GC-MS Chemical Profiles and Biological Activities of Three Citrus Essential Oils in Indonesia. Preprints 2024, 2024050629. https://doi.org/10.20944/preprints202405.0629.v1
Nuryandani, E.; Novitasari, E.; Abdurrahman, M. F.; Habibi, N.; Sefrienda, A. R.; Kurnianto, D.; Jasmadi, J.; Andriana, Y. Chemometric Analysis of GC-MS Chemical Profiles and Biological Activities of Three Citrus Essential Oils in Indonesia. Preprints2024, 2024050629. https://doi.org/10.20944/preprints202405.0629.v1
APA Style
Nuryandani, E., Novitasari, E., Abdurrahman, M. F., Habibi, N., Sefrienda, A. R., Kurnianto, D., Jasmadi, J., & Andriana, Y. (2024). Chemometric Analysis of GC-MS Chemical Profiles and Biological Activities of Three Citrus Essential Oils in Indonesia. Preprints. https://doi.org/10.20944/preprints202405.0629.v1
Chicago/Turabian Style
Nuryandani, E., Jasmadi Jasmadi and Yusuf Andriana. 2024 "Chemometric Analysis of GC-MS Chemical Profiles and Biological Activities of Three Citrus Essential Oils in Indonesia" Preprints. https://doi.org/10.20944/preprints202405.0629.v1
Abstract
Citrus species essential oils (EOs) are significant sources of bioactive compounds and demonstrate diverse therapeutic effects. However, limited documentation exists regarding the phytochemicals associated with their biological activities. This study aims to assess the antioxidant activity, plant inhibitory properties, and brine shrimp cytotoxic effects of EOs derived from three Citrus species: C. sinensis, C. limon, and C. hystrix. Utilizing chemometric analysis and gas chromatography-mass spectrometry (GC-MS) fingerprints, the volatile components contributing to antioxidant activity were elucidated. The peels of the Citrus samples were hydro-distillated to obtain EOs, and subsequently subjected to antioxidant, plant inhibitory, and brine shrimp cytotoxic assays. The results indicated that C. limon EO exhibited the highest antioxidant activity, while C. hystrix and C. sinensis EOs demonstrated pronounced inhibitory effects against Aetrmia salina and Lactuca sativa, respectively. GC-MS analysis facilitated the identification of key compounds in each EO. Principal component analysis (PCA) and hierarchy cluster analysis (HCA) effectively categorized Citrus EOs based on their antioxidant properties, highlighting the proximity of C. limon and C. sinensis. Among the identified compounds, D-limonene, α-Terpineol, Caryophyllene, (+)-3-Carene, β-Pinene, (-)-Spathulenol, trans-p-Mentha-1(7),8-dien-2-ol, and trans-Verbenol were the most discriminating compounds affected the antioxidant activity of C.limon and C. sinensis EOs.
Biology and Life Sciences, Biology and Biotechnology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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