Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Masld-Related Hepatocarcinoma: Special Features And Challenges

Version 1 : Received: 17 May 2024 / Approved: 20 May 2024 / Online: 20 May 2024 (13:07:32 CEST)

How to cite: Yagüe-Caballero, C.; Casas-Deza, D.; Espina-Cadena, S.; Pascual-Oliver, A.; Arbones-Mainar, J. M.; Bernal–Monterde, V. Masld-Related Hepatocarcinoma: Special Features And Challenges. Preprints 2024, 2024051278. https://doi.org/10.20944/preprints202405.1278.v1 Yagüe-Caballero, C.; Casas-Deza, D.; Espina-Cadena, S.; Pascual-Oliver, A.; Arbones-Mainar, J. M.; Bernal–Monterde, V. Masld-Related Hepatocarcinoma: Special Features And Challenges. Preprints 2024, 2024051278. https://doi.org/10.20944/preprints202405.1278.v1

Abstract

Metabolic Associated Steatohepatitis Liver Disease (MASLD) currently impacts a quarter of the global population and its prevalence is expected to increase in the future. As a result, the incidence of hepatocellular carcinoma associated with MASLD is also on the rise. Notably, hepatocellular carcinoma in this group does not always develop alongside liver cirrhosis, often leading to a more advanced stage at diagnosis. The challenge lies in accurately identifying patients who are at a higher risk of hepatocellular carcinoma to tailor screening processes effectively. Additionally, several therapeutic approaches are being explored to prevent hepatocellular carcinoma, although there are yet no universally accepted guidelines

Keywords

NAFLD; NASH; cirrhosis; hepatocellular carcinoma; surveillance; prevention

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

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