Review
Version 1
Preserved in Portico This version is not peer-reviewed
In Search of Feasible Interventions for the Prevention and Cure of Novel Coronavirus Disease 2019
Version 1
: Received: 20 March 2020 / Approved: 24 March 2020 / Online: 24 March 2020 (03:16:22 CET)
How to cite: Verma, S. K. In Search of Feasible Interventions for the Prevention and Cure of Novel Coronavirus Disease 2019 . Preprints 2020, 2020030353. https://doi.org/10.20944/preprints202003.0353.v1 Verma, S. K. In Search of Feasible Interventions for the Prevention and Cure of Novel Coronavirus Disease 2019 . Preprints 2020, 2020030353. https://doi.org/10.20944/preprints202003.0353.v1
Abstract
COVID-19 (coronavirus disease 2019) is a public health emergency of international concern caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As of this time, there is no known effective pharmaceutical, phytopharmaceutical or traditional medicine for cure or prevention of COVID-19, although it is urgently needed. In this review, based on the current understanding of the disease molecular mechanisms of novel Coronavirus SARS-CoV-2 and its closest relative SARS-CoV and other human Coronaviruses, I have identified some naturally occurring plant based substances and Ayurvedic medicinal herbs that could feasibly be tested as a matter of urgency for prevention as well as therapeutic option for COVID-19 in India and other parts of the world. I conclude that dried rhizome of Curcuma longa L. i.e. turmeric, and its active ingredient curcumin may be effective in preventing as well as cure the COVID-19 pandemic due to its proven antiviral activities, this however need to be tested by appropriate clinical trials as research priority.
Keywords
COVID-19; SARS-CoV-2; Severe Acute Respiratory Syndrome Coronavirus-2; Curcumin
Subject
Medicine and Pharmacology, Pathology and Pathobiology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments (6)
We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.
Leave a public commentSend a private comment to the author(s)
* All users must log in before leaving a comment
Commenter: Nisarg Joshi
The commenter has declared there is no conflict of interests.
Commenter: Ajay Kumar Yadav
The commenter has declared there is no conflict of interests.
Due to this lacking any treatment at this moment, home isolation, social distancing is only the option along with proper hygiene and immune boosters.
Commenter: Dr. Shreyas Goswami
The commenter has declared there is no conflict of interests.
Commenter: dileep shukla
The commenter has declared there is no conflict of interests.
Commenter: Mahendra K. Singh, Ph.D.
The commenter has declared there is no conflict of interests.
Commenter:
The commenter has declared there is no conflict of interests.
Today Government of India through its Press Information Bureau has released a press note and recommended Golden Milk i.e. Haldi Milk to fight against Chinese CORONA Virus.
Here is the link
https://pib.gov.in/PressReleseDetailm.aspx?PRID=1609524
Dr SK Verma