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Communication

Neurological Complications of Pandemic COVID-19: What Have We Got So Far?

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Isabelle Pastor Bandeira^*,Marco Antônio Machado Schlindwein,Leticia Caroline Breis,

Jean Pierre Schatzmann Peron,Marcus Vinicius Magno Gonçalves

Isabelle Pastor Bandeira^*,Marco Antônio Machado Schlindwein,Leticia Caroline Breis,

Jean Pierre Schatzmann Peron,Marcus Vinicius Magno Gonçalves

This version is not peer-reviewed

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Preprints on COVID-19 and SARS-CoV-2

Submitted:

17 April 2020

Posted:

17 April 2020

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Abstract

The recently emerged coronavirus named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2) is the newest threat to human health. It has already infected more than half a million people worldwide, leading to a lot of deaths. Although it causes mild flu-like disease in most patients, lethality may increase to more than 20% in elderly subjects, especially those with comorbidities, like hypertension, diabetes or lung and cardiac disease, and the mechanisms are still elusive. Common symptoms at the onset of illness are fever, cough, myalgia or fatigue, headache, and diarrhea or constipation. Interestingly, respiratory viruses have also placed themselves as relevant agents for CNS pathologies. Here we discuss several CNS related features, referred by several patients, especially at the beginning of the disease. Thus, we also discuss the possibility by which SARS-CoV-2 may affect the olfactive system of patients, either directly or indirectly.

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Subject: Medicine and Pharmacology - Neuroscience and Neurology

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