Preprint
Short Note
On the Importance of Population-Based Serological Surveys of SARS-CoV-2 Without Overlooking Their Inherent Uncertainties
This version is not peer-reviewed.
Submitted:
07 May 2020
Posted:
11 May 2020
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Abstract
This brief note aims to explain the scope in conducting large-scale serological surveys of SARS-CoV-2 to define the landscape of population immunity without overlooking the inherent uncertainty steaming from sampling design and diagnostic validity. The note completes with a succinct statistical appendix of simple methods for estimating prevalence from random population samples using imperfect diagnostic tests.
Keywords:
Serosurvey
; seroepidemiology
; seroprevalence
; sampling
; imperfect diagnostic test
; sensitivity
; specificity
; Coronavirus
Preprints on COVID-19 and SARS-CoV-2
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
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