Cardiovascular disease is the number one cause of death in the world and Quoting from WHO, around 31% of deaths in the world are caused by cardiovascular diseases and more than 75% of deaths occur in developing countries. The results of patients with cardiovascular disease produce many medical records that can be used for further patient management. This study aims to develop a method of data mining by grouping patients with cardiovascular disease to determine the level of patient complications in the two clusters. The method applied is principal component analysis (PCA) which aims to reduce the dimensions of the large data available and the techniques of data mining in the form of cluster analysis which implements the K-Medoids algorithm. The results of data reduction with PCA resulted in five new components with a cumulative proportion variance of 0.8311. The five new components are implemented for cluster formation using the K-Medoids algorithm which results in the form of two clusters with a silhouette coefficient of 0.35. Combination of techniques of Data reduction by PCA and the application of the K-Medoids clustering algorithm are new ways for grouping data of patients with cardiovascular disease based on the level of patient complications in each cluster of data generated.