This paper describes a new generation of computational intelligence founded on the ancient idea of compassion called Artificial Compassion. The creation of Artificial Compassion is the result of two coinciding historical developments. The first is the increasing discoveries of human sciences in new fields like neuroendocrinology and psychoneuroimmunology. This provides the spark for Artificial Compassion. For example, we once thought with certainty that our brain is fixed for life but neuropsychology and a device called the fMRI have shown it is “plastic”. It changes constantly throughout our lives in response to our experiences. Remarkably, we also now know it is changed for the better through positive emotions like compassion, kindness and happiness. So, too, are the immune, endocrine, genetic, cardio and neural systems influenced and changed by our emotional experiences. This new perspective on emotions and plasticity validates much of ancient wisdom in medical systems outside the west. Long held assumptions about emotion are unsuitable for humanity. The second development is ‘machine rub off’. We are in symbiotic relation with our devices today and we are plastic. We are changed by our interactions but many people have computer rage. We need Artificial Compassion to replace computer rage with positive plasticity.