Article
Version 1
Preserved in Portico This version is not peer-reviewed
Age-related Individual Behavioural Characteristics of Adult Wistar Rats
Version 1
: Received: 28 June 2021 / Approved: 30 June 2021 / Online: 30 June 2021 (10:57:00 CEST)
A peer-reviewed article of this Preprint also exists.
Sudakov, S.K.; Alekseeva, E.V.; Nazarova, G.A.; Bashkatova, V.G. Age-Related Individual Behavioural Characteristics of Adult Wistar Rats. Animals 2021, 11, 2282. Sudakov, S.K.; Alekseeva, E.V.; Nazarova, G.A.; Bashkatova, V.G. Age-Related Individual Behavioural Characteristics of Adult Wistar Rats. Animals 2021, 11, 2282.
Abstract
The aim of this work was to study age-related changes in the behaviour of adult Wistar rats using the open field (OF) and elevated plus maze (EPM) tests. Behavioural changes related to motor activity and anxiety were of particular interest. Results showed that as male and female rats progressed from 2 to 5 months of age there was a decrease in the level of motor and exploratory activities, and an increase in the level of anxiety. Age-related changes were dependent upon initial individual characteristics of behaviour. For example, animals that demonstrated high motor activity at 2 months become significantly less active by 5 months, and animals that showed a low level of anxiety at 2 months become more anxious by 5 months. Low-activity and high-anxiety rats did not show any significant age-related changes in OF and EPM tests from 2 to 5 months of age, except for a decrease in the number of rearings in EPM. Significant individual differences in the behaviour of rats in OF and EPM tests observed at 2 months were not apparent by 5 months.
Keywords
age; behaviour; open field; physical activity; anxiety; Wistar rat.
Subject
Social Sciences, Psychology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments (0)
We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.
Leave a public commentSend a private comment to the author(s)
* All users must log in before leaving a comment