Version 1
: Received: 7 April 2022 / Approved: 8 April 2022 / Online: 8 April 2022 (08:48:36 CEST)
How to cite:
Rudolphi-Solero, T.; Triviño-Ibáñez, E. M.; Martínez-Barbero, J. P.; Cordero-Tous, N.; Chamorro-Santos, C. E.; Rodríguez-Fernández, A.; Gómez-Río, M. M. [18F]Fluorocholine PET/CT False Positive: Foreign Body Reaction Mimicking Low-Grade Glioma Progression. Preprints2022, 2022040076. https://doi.org/10.20944/preprints202204.0076.v1
Rudolphi-Solero, T.; Triviño-Ibáñez, E. M.; Martínez-Barbero, J. P.; Cordero-Tous, N.; Chamorro-Santos, C. E.; Rodríguez-Fernández, A.; Gómez-Río, M. M. [18F]Fluorocholine PET/CT False Positive: Foreign Body Reaction Mimicking Low-Grade Glioma Progression. Preprints 2022, 2022040076. https://doi.org/10.20944/preprints202204.0076.v1
Rudolphi-Solero, T.; Triviño-Ibáñez, E. M.; Martínez-Barbero, J. P.; Cordero-Tous, N.; Chamorro-Santos, C. E.; Rodríguez-Fernández, A.; Gómez-Río, M. M. [18F]Fluorocholine PET/CT False Positive: Foreign Body Reaction Mimicking Low-Grade Glioma Progression. Preprints2022, 2022040076. https://doi.org/10.20944/preprints202204.0076.v1
APA Style
Rudolphi-Solero, T., Triviño-Ibáñez, E. M., Martínez-Barbero, J. P., Cordero-Tous, N., Chamorro-Santos, C. E., Rodríguez-Fernández, A., & Gómez-Río, M. M. (2022). [18F]Fluorocholine PET/CT False Positive: Foreign Body Reaction Mimicking Low-Grade Glioma Progression. Preprints. https://doi.org/10.20944/preprints202204.0076.v1
Chicago/Turabian Style
Rudolphi-Solero, T., Antonio Rodríguez-Fernández and Manuel María Gómez-Río. 2022 "[18F]Fluorocholine PET/CT False Positive: Foreign Body Reaction Mimicking Low-Grade Glioma Progression" Preprints. https://doi.org/10.20944/preprints202204.0076.v1
Abstract
A right frontoparietal neoplastic lesion was found in a young-aged patient with analgesic refractory headache. Surgical resection was performed, and the pathologist analysis turned out a cellular ependymoma with signs of anaplasia. In the follow-up, a MRI showed a suspicious lesion, so a [18F]Fluorocholine PET/CT was performed. An increased uptake was described in the right parietal region on the margin of residual cystic lesion. The patient got a complete resection which was confirmed later by MR. In the pathology analysis, a focally congestive cerebral parenchyma with a central histiocytic reaction to foreign body area was described. Foreign body reaction in brain tissue is a very rare immune response that has not been well studied. Haemostatic material has been reported as a possible trigger of this response in other organs and could be detected by [18F]FDG PET/CT. Following the experience of the current case report, [18F]Fluorocholine PET/CT could also show a false positive related to foreign body reaction.
Keywords
Foreign Body Reaction; deshydroxy-(18F) fluorocholine; Positron Emission Tomography; Low-grade glioma; Haemostatic material
Subject
Medicine and Pharmacology, Oncology and Oncogenics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.