Version 1
: Received: 27 April 2023 / Approved: 28 April 2023 / Online: 28 April 2023 (03:23:54 CEST)
How to cite:
Gavanji, S.; Bakhtari, A.; Abdel-latif, R.; Bencurova, E.; Othman, E. M. In Vitro and in vivo Experimental Approaches for Antidiabetic Activity Assessment: A Methodological Review. Preprints2023, 2023041092. https://doi.org/10.20944/preprints202304.1092.v1
Gavanji, S.; Bakhtari, A.; Abdel-latif, R.; Bencurova, E.; Othman, E. M. In Vitro and in vivo Experimental Approaches for Antidiabetic Activity Assessment: A Methodological Review. Preprints 2023, 2023041092. https://doi.org/10.20944/preprints202304.1092.v1
Gavanji, S.; Bakhtari, A.; Abdel-latif, R.; Bencurova, E.; Othman, E. M. In Vitro and in vivo Experimental Approaches for Antidiabetic Activity Assessment: A Methodological Review. Preprints2023, 2023041092. https://doi.org/10.20944/preprints202304.1092.v1
APA Style
Gavanji, S., Bakhtari, A., Abdel-latif, R., Bencurova, E., & Othman, E. M. (2023). <em>In Vitro </em>and <em>in vivo</em> Experimental Approaches for Antidiabetic Activity Assessment: A Methodological Review. Preprints. https://doi.org/10.20944/preprints202304.1092.v1
Chicago/Turabian Style
Gavanji, S., Elena Bencurova and Eman M. Othman. 2023 "<em>In Vitro </em>and <em>in vivo</em> Experimental Approaches for Antidiabetic Activity Assessment: A Methodological Review" Preprints. https://doi.org/10.20944/preprints202304.1092.v1
Abstract
Diabetes mellitus is a global health issue that necessitates the development of novel therapeutic approaches. Today numerous experimental methods have been used and set up to evaluate novel drugs with antidiabetic effects. In addition, several research studies have been done to induce diabetes under in vitro and in vivo conditions, but only a small number of these efforts are currently in a usable stage. This review aims to provide useful guidance for researchers who seek to evaluate the antidiabetic potential of drugs, agents, or new medications using the standard methods published by authorities and academics worldwide organizations and research centers. In this review, we collected 132 relevant articles from prominent databases such as PubMed, ScienceDirect, Scopus and others to summarize in vitro and in vivo experimental validation of antidiabetic treatment from 1943 to present.
Keywords
Diabetes mellitus; antidiabetic activity; in vitro; in vivo; assays
Subject
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.