Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

First Description of a Mixed Brugada Pattern in Inferior Leads

Version 1 : Received: 22 May 2023 / Approved: 25 May 2023 / Online: 25 May 2023 (08:56:31 CEST)

A peer-reviewed article of this Preprint also exists.

Bermejo Valdés, A. J., Gutiérrez, S. I., & Ruiz, B. T. (2024). First description of a mixed Brugada pattern in inferior leads. Journal of Clinical Cardiology and Cardiovascular Interventions, 7(4). doi: 10.31579/2641-0419/369. Bermejo Valdés, A. J., Gutiérrez, S. I., & Ruiz, B. T. (2024). First description of a mixed Brugada pattern in inferior leads. Journal of Clinical Cardiology and Cardiovascular Interventions, 7(4). doi: 10.31579/2641-0419/369.

Abstract

Brugada Syndrome is a cardiac channelopathy closely related to lethal arrhythmias and sudden death in people without underlying structural pathology. The diagnosis is usually assumed with electrocardiographic patterns strictly limited to the right precordial leads, V1 or V2; but this is not so at all. In our article, we describe the clinical case of a patient with a novel and different electrocardiographic presentation: the typical diagnostic pattern was presented in a lower lead of the electrocardiogram, and next to it, another pattern was presented in a contiguous lead. In addition, we propose the possible association of a structural pathology (non-compaction cardiomyopathy) with Brugada Syndrome, since both share a possible common genetic origin in the SCN5A gene.

Keywords

Brugada Syndrome; channelopathy; arrhythmias

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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