Review
Version 1
Preserved in Portico This version is not peer-reviewed
Association between Inflamatory Responses and Mitochondrial Dynamics in Salmonella Infection
Version 1
: Received: 30 September 2023 / Approved: 1 October 2023 / Online: 1 October 2023 (07:55:51 CEST)
How to cite: K, H.; Pandey, R. P. Association between Inflamatory Responses and Mitochondrial Dynamics in Salmonella Infection. Preprints 2023, 2023100005. https://doi.org/10.20944/preprints202310.0005.v1 K, H.; Pandey, R. P. Association between Inflamatory Responses and Mitochondrial Dynamics in Salmonella Infection. Preprints 2023, 2023100005. https://doi.org/10.20944/preprints202310.0005.v1
Abstract
Salmonella is the intracellular pathogen and etiological known for the cause of asymptomatic carriage, gastroenteritis, systemic disease (typhoid fever), in severe cases death may also occur. Altered function of mitochondria due to Salmonella infection impacts the immune response. Mitochondria which are recognized as the “powerhouse” of the cells are also know to play central role in the immune metabolism. Mitochondrial dynamics such as fusion, fission, signaling, transport and mitophagy influences the immune system and also maintains the cellular integrity. Mitochondrial DNA and Reactive oxygen species formation also elicits the inflammatory responses. This review discusses the immune metabolism and effect of altered mitochondrial dynamics in case of Salmonella infection.
Keywords
Mitochondria; immune response; activation; secretion; phagocytic
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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