Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Secondary Metabolites from Genus Eurotium and Their Biological Activities

Version 1 : Received: 27 October 2023 / Approved: 27 October 2023 / Online: 30 October 2023 (08:37:36 CET)

A peer-reviewed article of this Preprint also exists.

Deng, J.; Li, Y.; Yuan, Y.; Yin, F.; Chao, J.; Huang, J.; Liu, Z.; Wang, K.; Zhu, M. Secondary Metabolites from the Genus Eurotium and Their Biological Activities. Foods 2023, 12, 4452. Deng, J.; Li, Y.; Yuan, Y.; Yin, F.; Chao, J.; Huang, J.; Liu, Z.; Wang, K.; Zhu, M. Secondary Metabolites from the Genus Eurotium and Their Biological Activities. Foods 2023, 12, 4452.

Abstract

Eurotium is the teleomorph genus associated with section Aspergillus. Eurotium comprises approximately 20 species, which are widely distributed in nature and human environments. Eurotium is usually the key microorganism for the ferment ation of traditional food, such as Fuzhuan brick tea, Liupao tea, Meju, and Karebushi, thus Eurotium is an important fungus in food industry. Eurotium has been extensively studied because they contain a series of interesting, structurally diverse, and biologically important secondary metabolites, including anthraquinones, benzaldehyde derivatives, and indol diketopiperazine alkaloids. These secondary metabolites have shown multiple biological activities, including antioxidative, antimicrobial, cytotoxic, antitumor, insecticidal, antimalarial, and anti-inflammatory activities. This study presents an up-to-date review of the phytochemistry and biological activities of all Eurotium species. This review will provide the recent advances on the secondary metabolites and their bioactivities in genus Eurotium for the first time and serve as a database for future research and drug development from the genus Eurotium.

Keywords

Eurotium; Eurotium cristatum; secondary metabolites; anthraquinones; benzaldehyde derivatives; biological activity

Subject

Biology and Life Sciences, Food Science and Technology

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