Luciano, G.; Vignolo, M.; Galante, D.; D’Arrigo, C.; Furlani, F.; Montesi, M.; Panseri, S. Designing and Manufacturing of Biocompatible Hydroxyapatite and Sodium Trisilicate Scaffolds by Ordinary Domestic Microwave Oven. Compounds2024, 4, 106-118.
Luciano, G.; Vignolo, M.; Galante, D.; D’Arrigo, C.; Furlani, F.; Montesi, M.; Panseri, S. Designing and Manufacturing of Biocompatible Hydroxyapatite and Sodium Trisilicate Scaffolds by Ordinary Domestic Microwave Oven. Compounds 2024, 4, 106-118.
Luciano, G.; Vignolo, M.; Galante, D.; D’Arrigo, C.; Furlani, F.; Montesi, M.; Panseri, S. Designing and Manufacturing of Biocompatible Hydroxyapatite and Sodium Trisilicate Scaffolds by Ordinary Domestic Microwave Oven. Compounds2024, 4, 106-118.
Luciano, G.; Vignolo, M.; Galante, D.; D’Arrigo, C.; Furlani, F.; Montesi, M.; Panseri, S. Designing and Manufacturing of Biocompatible Hydroxyapatite and Sodium Trisilicate Scaffolds by Ordinary Domestic Microwave Oven. Compounds 2024, 4, 106-118.
Abstract
In this work we present a versatile, rapid, and low-cost manufacturing technique to develop bioceramic scaffolds that could enhance bone tissue regeneration via microwave preparation using a commercial microwave oven. The scaffolds were prepared combining hydroxyapatite and water glass (sodium trisilicate solution), foamed by using a microwaves oven and then characterized by means of SEM-EDS, mechanical properties, infrared spectroscopy (ATR-FTIR), density and stability test in water. Furthermore, in vitro tests were performed to verify the affinity of osteoclast cells versus the so prepared scaffold. The morphology of the samples showed interconnected pores suitable for promoting tissue regeneration and vascularization while specific mechanical properties were preserved. The physicochemical characterization and the in vitro tests presented promising results for bone regenerative applications.
Keywords
Microwave; Foaming Bone Scaffold; Sodium Trisilicate; Hydroxyapatite; In Vitro Tests
Subject
Chemistry and Materials Science, Biomaterials
Copyright:
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