Pontes, K.F.M.; Nardozza, L.M.M.; Peixoto, A.B.; Werner, H.; Tonni, G.; Granese, R.; Araujo Júnior, E. Cytomegalovirus and Pregnancy: A Narrative Review. J. Clin. Med.2024, 13, 640.
Pontes, K.F.M.; Nardozza, L.M.M.; Peixoto, A.B.; Werner, H.; Tonni, G.; Granese, R.; Araujo Júnior, E. Cytomegalovirus and Pregnancy: A Narrative Review. J. Clin. Med. 2024, 13, 640.
Pontes, K.F.M.; Nardozza, L.M.M.; Peixoto, A.B.; Werner, H.; Tonni, G.; Granese, R.; Araujo Júnior, E. Cytomegalovirus and Pregnancy: A Narrative Review. J. Clin. Med.2024, 13, 640.
Pontes, K.F.M.; Nardozza, L.M.M.; Peixoto, A.B.; Werner, H.; Tonni, G.; Granese, R.; Araujo Júnior, E. Cytomegalovirus and Pregnancy: A Narrative Review. J. Clin. Med. 2024, 13, 640.
Abstract
Cytomegalovirus (CMV) infection is the most common congenital infection worldwide, affecting between 0.7% and 1% of all live births. Approximately 11% of infected newborns are symptomatic at birth, and between 30% and 40% of these are at risk of developing long-term neurological sequelae. Until recently, the lack of an effective treatment did not justify universal testing of pregnant women. In recent years, however, valacyclovir at a dose of 8 g/day has been shown to be effective in preventing vertical transmission, and ganciclovir has been shown to be effective in preventing long-term sequelae in the treatment of symptomatic neonates. The aim of this article is to review congenital CMV infection, from its epidemiology to its treatment, using the most recent studies in the literature, and to help in the decision to modify protocols for universal testing of pregnant women according to the possibilities of each locality.
Medicine and Pharmacology, Obstetrics and Gynaecology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
,
,
,
,
,
