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Trajectories of State-Level Sepsis-Related Mortality by Race and Ethnicity Group in the United States
Version 1
: Received: 22 March 2024 / Approved: 25 March 2024 / Online: 25 March 2024 (11:11:17 CET)
A peer-reviewed article of this Preprint also exists.
Oud, L.; Garza, J. Trajectories of State-Level Sepsis-Related Mortality by Race and Ethnicity Group in the United States. J. Clin. Med. 2024, 13, 2848. Oud, L.; Garza, J. Trajectories of State-Level Sepsis-Related Mortality by Race and Ethnicity Group in the United States. J. Clin. Med. 2024, 13, 2848.
Abstract
Background: Recent reports on the national temporal trends of sepsis-related mortality in the United States (US) suggested outcome improvement in several race and ethnicity groups. However, it is unknown whether national data reflect state-level trajectories.
Methods: We used the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research Multiple Cause of Death dataset to identify all decedents with sepsis in the US during 2010-2019. Negative binomial regression models were fit to estimate national and state-level trends of age-adjusted sepsis-related mortality rates within race and ethnicity groups.
Results: There were 1,852,610 sepsis-related deaths in the US during 2010-2019. Nationally, sepsis-related mortality rates decreased among Blacks and Asians, were unchanged among Hispanics and Native Americans, and rose among Whites. The percent of states with similar trends were 30.0% among Blacks, 32.1% among Asians, 74.3% among Hispanics, 75.0% among Native Americans, and 66.7%% among Whites, while trending in opposite direction from 3.6% among Asians to 15.0% among Blacks.
Conclusions: National trends in sepsis-related mortality in the US did not represent state-level trajectories in race and ethnicity groups. Gains in sepsis outcomes among race and ethnicity groups at the national level were not shared equitably at the state level.
Keywords
Disparity; ethnicity; mortality; race; sepsis; states
Subject
Public Health and Healthcare, Public Health and Health Services
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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