Review
Version 1
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Peritoneum Adhesion Genetic Determinism
Version 1
: Received: 13 April 2024 / Approved: 15 April 2024 / Online: 15 April 2024 (13:49:10 CEST)
How to cite: Lungu, M.; Candussi, I.-L.; Lungu, C. N.; Mehedinti, M. C. Peritoneum Adhesion Genetic Determinism. Preprints 2024, 2024040968. https://doi.org/10.20944/preprints202404.0968.v1 Lungu, M.; Candussi, I.-L.; Lungu, C. N.; Mehedinti, M. C. Peritoneum Adhesion Genetic Determinism. Preprints 2024, 2024040968. https://doi.org/10.20944/preprints202404.0968.v1
Abstract
Injury to the peritoneum during surgery is followed by a healing process that frequently results in the attachment of adjacent organs by a fibrous mass, referred to commonly as adhesions. Because injuries to the peritoneum during surgery are inevitable, one must understand the mechanisms of adhesion formation to prevent its occurrence. This requires a thorough understanding of the molecular sequence that results in the attachment of injured peritoneum and the development of fibrous tissue. Recent data show that fibroblasts from the injured peritoneum may play a critical role in forming adhesion tissues. Therefore, identifying changes in gene expression patterns in the peritoneal fibroblasts during the process may provide clues to the mechanisms by which adhesion develops. This review presents many papers discussing genes implied in peritoneal adhesion.
Keywords
peritoneum, adhesion , adhesion genes, peritonitis, reintervention.
Subject
Medicine and Pharmacology, Medicine and Pharmacology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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