Version 1
: Received: 8 May 2024 / Approved: 8 May 2024 / Online: 8 May 2024 (17:39:02 CEST)
How to cite:
Villalobos-González, C. E.; Gómez-Carmona, C. D.; Sánchez-Ureña, B.; Azofeifa-Mora, C.; Rojas-Valverde, D. Prospective Analysis of Cannabidiol's Effectiveness in Post-Exercise Recovery: An integrative Systematic Review and Research Agenda. Preprints2024, 2024050517. https://doi.org/10.20944/preprints202405.0517.v1
Villalobos-González, C. E.; Gómez-Carmona, C. D.; Sánchez-Ureña, B.; Azofeifa-Mora, C.; Rojas-Valverde, D. Prospective Analysis of Cannabidiol's Effectiveness in Post-Exercise Recovery: An integrative Systematic Review and Research Agenda. Preprints 2024, 2024050517. https://doi.org/10.20944/preprints202405.0517.v1
Villalobos-González, C. E.; Gómez-Carmona, C. D.; Sánchez-Ureña, B.; Azofeifa-Mora, C.; Rojas-Valverde, D. Prospective Analysis of Cannabidiol's Effectiveness in Post-Exercise Recovery: An integrative Systematic Review and Research Agenda. Preprints2024, 2024050517. https://doi.org/10.20944/preprints202405.0517.v1
APA Style
Villalobos-González, C. E., Gómez-Carmona, C. D., Sánchez-Ureña, B., Azofeifa-Mora, C., & Rojas-Valverde, D. (2024). Prospective Analysis of Cannabidiol's Effectiveness in Post-Exercise Recovery: An integrative Systematic Review and Research Agenda. Preprints. https://doi.org/10.20944/preprints202405.0517.v1
Chicago/Turabian Style
Villalobos-González, C. E., Christian Azofeifa-Mora and Daniel Rojas-Valverde. 2024 "Prospective Analysis of Cannabidiol's Effectiveness in Post-Exercise Recovery: An integrative Systematic Review and Research Agenda" Preprints. https://doi.org/10.20944/preprints202405.0517.v1
Abstract
Recovery between physical efforts is essential for optimal performance in sports. Dietary supplements like cannabidiol (CBD) have been proposed to facilitate recovery and performance optimization. This systematic review aimed to: a) systematize the scientific evidence on CBD for recovery, b) associate CBD's biomedical properties with those required for optimal fatigue recovery, and c) recommend a future research agenda. Searches across databases identified 70 relevant studies from 1990-2022, including 38.6% preclinical, 31.4% clinical trials, and 30.0% reviews/meta-analyses across various populations like mice, rats, epileptics, and athletes. CBD demonstrated potentially beneficial properties for athlete recovery such as anti-inflammatory, neuroprotective, anxiolytic, and analgesic effects with doses ranging from 5-600mg administered orally, intravenously, and via other routes. However, rigorous confirmatory research specifically in athlete populations is lacking. While CBD appears promising for facilitating recovery and performance optimization, further randomized placebo-controlled trials are needed to test the acute and chronic effects of different CBD dosing regimens in athletes. Future research should focus on elucidating CBD's physiological mechanisms of action as they relate to post-exercise recovery, as well as its comparative effectiveness versus conventional medications and therapies. Advancing our understanding of CBD's role in athlete recovery could provide new therapeutic strategies to optimize recovery and performance.
Keywords
recovery; cannabidiol; anti-inflammatory; dietary supplements; sport
Subject
Public Health and Healthcare, Physical Therapy, Sports Therapy and Rehabilitation
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.