Zaffanello, M.; Ferrante, G.; Piazza, M.; Nosetti, L.; Tenero, L.; Piacentini, G. Exploring the Relationship between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review. Adv. Respir. Med.2024, 92, 300-317.
Zaffanello, M.; Ferrante, G.; Piazza, M.; Nosetti, L.; Tenero, L.; Piacentini, G. Exploring the Relationship between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review. Adv. Respir. Med. 2024, 92, 300-317.
Zaffanello, M.; Ferrante, G.; Piazza, M.; Nosetti, L.; Tenero, L.; Piacentini, G. Exploring the Relationship between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review. Adv. Respir. Med.2024, 92, 300-317.
Zaffanello, M.; Ferrante, G.; Piazza, M.; Nosetti, L.; Tenero, L.; Piacentini, G. Exploring the Relationship between Inhaled Corticosteroid Usage, Asthma Severity, and Sleep-Disordered Breathing: A Systematic Literature Review. Adv. Respir. Med. 2024, 92, 300-317.
Abstract
Additionally, the characteristics of inhaled corticosteroids (inhaled particle sizes) may influence the risk of sleep apnea. In children, the severity of asthma plays a crucial role in influencing the prevalence of sleep apnea, while using inhaled corticosteroids seems to be a less relevant risk factor compared to adults. The overall risk of bias was categorized as high or with some concerns in 100% of the studies analyzed. Each study identified at least one form of bias that raised significant concerns. Studies showed a complex relationship between inhaled corticosteroids use, asthma severity, and the onset of sleep apnea. Further studies are needed.
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