Version 1
: Received: 3 July 2024 / Approved: 3 July 2024 / Online: 4 July 2024 (09:01:32 CEST)
How to cite:
Ortega-Vidal, J.; Mut-Salud, N.; De la Torre, J. M.; Altarejos, J.; Salido, S. Chemical Characterization of Pruning Wood Extracts from Six Japanese Plum (Prunus salicina Lindl.) Cultivars and their Antitumor Activity. Preprints2024, 2024070358. https://doi.org/10.20944/preprints202407.0358.v1
Ortega-Vidal, J.; Mut-Salud, N.; De la Torre, J. M.; Altarejos, J.; Salido, S. Chemical Characterization of Pruning Wood Extracts from Six Japanese Plum (Prunus salicina Lindl.) Cultivars and their Antitumor Activity. Preprints 2024, 2024070358. https://doi.org/10.20944/preprints202407.0358.v1
Ortega-Vidal, J.; Mut-Salud, N.; De la Torre, J. M.; Altarejos, J.; Salido, S. Chemical Characterization of Pruning Wood Extracts from Six Japanese Plum (Prunus salicina Lindl.) Cultivars and their Antitumor Activity. Preprints2024, 2024070358. https://doi.org/10.20944/preprints202407.0358.v1
APA Style
Ortega-Vidal, J., Mut-Salud, N., De la Torre, J. M., Altarejos, J., & Salido, S. (2024). Chemical Characterization of Pruning Wood Extracts from Six Japanese Plum (Prunus salicina Lindl.) Cultivars and their Antitumor Activity. Preprints. https://doi.org/10.20944/preprints202407.0358.v1
Chicago/Turabian Style
Ortega-Vidal, J., Joaquín Altarejos and Sofia Salido. 2024 "Chemical Characterization of Pruning Wood Extracts from Six Japanese Plum (Prunus salicina Lindl.) Cultivars and their Antitumor Activity" Preprints. https://doi.org/10.20944/preprints202407.0358.v1
Abstract
Japanese plum tree (Prunus salicina Lindl.) is mainly cultivated in temperate areas of China and some European countries. Certain amounts of wood (from pruning works) are generated every year from this crop of worldwide commercial significance. The main objective of this work was to value this agricultural woody residue, for which the chemical composition of pruning wood extracts from six Japanese plum cultivars was investigated, and the antiproliferative activity of extracts and pure phenolics present in those extracts was measured. For the chemical characterization, total phenolic content and DPPH radical-scavenging assays and HPLC‒DAD/ESI‒MS analyses were performed, the procyanidin (‒)-ent-epicatechin-(2α→O→7,4α→8)-epicatechin (5) and the propelargonidin (+)-epiafzelechin-(2β→O→7,4β→8)-epicatechin (7) being the major components of the wood extracts. Some quantitative differences were found among plum cultivars, and the content of proanthocyanidins ranged from 1.50 (cv. ‘Fortune’) to 4.44 (cv. ‘Showtime’) mg/g of dry wood. Regarding the antitumoral activiy, eight wood extracts and four phenolic compounds were evaluated in MCF-7 cells after 48 h of induction, showing the wood extract from cv. ‘Songold’ and (‒)-annphenone (3) the best antiproliferative activity (IC50: 424 ppm and 405 ppm, respectively).
Chemistry and Materials Science, Organic Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
