Version 1
: Received: 2 July 2024 / Approved: 4 July 2024 / Online: 4 July 2024 (09:17:09 CEST)
How to cite:
Bacour, N.; Theijse, R. T.; Grewal, N.; Klautz, R. Racial and Ethnic Disparities in the Presentation and Outcome of Patients with Thoracic Aortic Aneurysms. Preprints2024, 2024070416. https://doi.org/10.20944/preprints202407.0416.v1
Bacour, N.; Theijse, R. T.; Grewal, N.; Klautz, R. Racial and Ethnic Disparities in the Presentation and Outcome of Patients with Thoracic Aortic Aneurysms. Preprints 2024, 2024070416. https://doi.org/10.20944/preprints202407.0416.v1
Bacour, N.; Theijse, R. T.; Grewal, N.; Klautz, R. Racial and Ethnic Disparities in the Presentation and Outcome of Patients with Thoracic Aortic Aneurysms. Preprints2024, 2024070416. https://doi.org/10.20944/preprints202407.0416.v1
APA Style
Bacour, N., Theijse, R. T., Grewal, N., & Klautz, R. (2024). Racial and Ethnic Disparities in the Presentation and Outcome of Patients with Thoracic Aortic Aneurysms. Preprints. https://doi.org/10.20944/preprints202407.0416.v1
Chicago/Turabian Style
Bacour, N., Nimrat Grewal and R Klautz. 2024 "Racial and Ethnic Disparities in the Presentation and Outcome of Patients with Thoracic Aortic Aneurysms" Preprints. https://doi.org/10.20944/preprints202407.0416.v1
Abstract
Background/Objectives: Thoracic aortic aneurysms (TAAs) pose critical health risks, often asymptomatic until a rupture or dissection occurs. Current guidelines recommend surgical repair based on specific aortic diameters and risk factors, emphasizing the importance of early detection and intervention. Despite established clinical risk factors for early detection in TAAs, the influence of racial and ethnic disparities on TAAs remains underexplored. This study aims to provide a comprehensive summary of existing research on racial and ethnic disparities in the presentation and outcomes of TAAs. Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, with the objective of exploring racial and ethnic differences in the presentation and surgical outcomes of patients with TAAs. Results: The findings demonstrated that black patients were younger at presentation and had a higher incidence of ruptured TAAs than non-black patients. Furthermore, compared to non-black patients, black patients had higher rates of cardiac arrhythmia and COPD, as well as comorbidities such as diabetes, hypertension, and renal insufficiency. For black patients undergoing open surgery, the surgical results showed improved 5-year survival rates after repair but higher perioperative mortality rates. All-cause or in-hospital mortality did not significantly differ between the racial groups, according to four studies. Discussion: This review highlights significant racial and ethnic disparities in TAA presentation and outcomes, underscoring the need for personalized risk stratification models. Standardized racial and ethnic definitions are essential for consistent and reliable research. Future studies should focus on refining risk assessment models to enhance diagnostic and therapeutic strategies, ultimately improving patient outcomes across diverse populations.
Keywords
Thoracic Aortic Aneurysms
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
