Version 1
: Received: 8 July 2024 / Approved: 8 July 2024 / Online: 9 July 2024 (05:45:12 CEST)
How to cite:
Muleshkova, T.; Bazukyan, I.; Papadimitriou, K.; Gotcheva, V.; Angelov, A.; Dimov, S. G. Exploring the Multifaceted Genus Acinetobacter: The Facts, the Concerns and the Opportunities. Preprints2024, 2024070683. https://doi.org/10.20944/preprints202407.0683.v1
Muleshkova, T.; Bazukyan, I.; Papadimitriou, K.; Gotcheva, V.; Angelov, A.; Dimov, S. G. Exploring the Multifaceted Genus Acinetobacter: The Facts, the Concerns and the Opportunities. Preprints 2024, 2024070683. https://doi.org/10.20944/preprints202407.0683.v1
Muleshkova, T.; Bazukyan, I.; Papadimitriou, K.; Gotcheva, V.; Angelov, A.; Dimov, S. G. Exploring the Multifaceted Genus Acinetobacter: The Facts, the Concerns and the Opportunities. Preprints2024, 2024070683. https://doi.org/10.20944/preprints202407.0683.v1
APA Style
Muleshkova, T., Bazukyan, I., Papadimitriou, K., Gotcheva, V., Angelov, A., & Dimov, S. G. (2024). Exploring the Multifaceted Genus Acinetobacter: The Facts, the Concerns and the Opportunities. Preprints. https://doi.org/10.20944/preprints202407.0683.v1
Chicago/Turabian Style
Muleshkova, T., Angel Angelov and Svetoslav G. Dimov. 2024 "Exploring the Multifaceted Genus Acinetobacter: The Facts, the Concerns and the Opportunities" Preprints. https://doi.org/10.20944/preprints202407.0683.v1
Abstract
In recent years, the research community has been interested in members of the Acinetobacter genus mainly because of their role as causative agents of nosocomial infections. However, this rich-in-species genus has been proven to play a significant role in different biotechnological processes, such as bioremediation and fermented foods production. To partially fill the lack of information on Acinetobacter’s dualistic nature, in this review, based on literature data, we attempt to summarize the available information on the different roles the members of the genus play by considering their genetic constitution and metabolic properties. We found pieces of evidence of genetic divergence between the pathogenic and non-pathogenic species and strains, which can be explained by their high adaptability to the different ecological niches. In turn, this adaptability could result from intrinsic genetic variability due to mechanisms of horizontal genetic transfer, as well as high mutability determined by the expression of error-prone DNA polymerases. Yet, further studies are needed, especially whole-genome sequencing of non-pathogenic isolates, which for the moment are relatively scarce.
Keywords
Acinetobacter genus; pathogenic and non-pathogenic species and strains; genetic divergence
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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