Version 1
: Received: 8 July 2024 / Approved: 8 July 2024 / Online: 9 July 2024 (07:00:06 CEST)
How to cite:
Grant, W. B.; Martinez, P. French Cancer Incidence and Mortality from 2007 to 2016 in Terms of Solar UVB and Obesity: An Ecological Study. Preprints2024, 2024070701. https://doi.org/10.20944/preprints202407.0701.v1
Grant, W. B.; Martinez, P. French Cancer Incidence and Mortality from 2007 to 2016 in Terms of Solar UVB and Obesity: An Ecological Study. Preprints 2024, 2024070701. https://doi.org/10.20944/preprints202407.0701.v1
Grant, W. B.; Martinez, P. French Cancer Incidence and Mortality from 2007 to 2016 in Terms of Solar UVB and Obesity: An Ecological Study. Preprints2024, 2024070701. https://doi.org/10.20944/preprints202407.0701.v1
APA Style
Grant, W. B., & Martinez, P. (2024). French Cancer Incidence and Mortality from 2007 to 2016 in Terms of Solar UVB and Obesity: An Ecological Study. Preprints. https://doi.org/10.20944/preprints202407.0701.v1
Chicago/Turabian Style
Grant, W. B. and Pierrick Martinez. 2024 "French Cancer Incidence and Mortality from 2007 to 2016 in Terms of Solar UVB and Obesity: An Ecological Study" Preprints. https://doi.org/10.20944/preprints202407.0701.v1
Abstract
Many risk-modifying factors affect cancer incidence and mortality rates. We present an ecological study of incidence and/or mortality rates for cancers during 2007–2016 of 17 anatomical sites with respect to solar ultraviolet-B (UVB) doses and obesity prevalence. Solar UVB reduces cancer risk by producing vitamin D, which has many mechanisms to reduce risk of cancer incidence, progression, and metastasis. Obesity increases cancer risk through several mechanisms, including increased systemic inflammation. Data were averaged for 12 geographical regions. Solar UVB doses were significantly inversely correlated with mortality rates for five cancers for males and four for females. Obesity prevalence was directly correlated with mortality rates for three cancers for males and seven for females. The population attributable fraction of cancer mortality rates ascribed to low solar UVB dose was 0.03 for both males and females, whereas that for obesity prevalence was 0.05 for males and 0.08 for females. Thus, cancer mortality rates in France could be reduced through vitamin D supplementation and reducing the prevalence of obesity. Doing so also could reduce risk of other adverse health outcomes.
Keywords
cancer; diet; ecological study; incidence rate; mortality rate; obesity; risk; solar UVB; smoking; vitamin D
Subject
Public Health and Healthcare, Health Policy and Services
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
