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Preservation of Vocal Function in Amyotrophic Lateral Sclerosis (ALS) Patients Following Percutaneous Dilatational Tracheostomy (PDT) and Adjuvant Therapies
Yoo, J.-K.; Kwon, S.-H.; Yoon, S.-H.; Lee, J.-E.; Jung, J.-H.; Jun, J.-E.; Lee, S.-Y. Preservation of Vocal Function in Amyotrophic Lateral Sclerosis (ALS) Patients Following Percutaneous Dilatational Tracheostomy (PDT) and Adjuvant Therapies. Preprints2024, 2024070894. https://doi.org/10.20944/preprints202407.0894.v1
APA Style
Yoo, J. K., Kwon, S. H., Yoon, S. H., Lee, J. E., Jung, J. H., Jun, J. E., & Lee, S. Y. (2024). Preservation of Vocal Function in Amyotrophic Lateral Sclerosis (ALS) Patients Following Percutaneous Dilatational Tracheostomy (PDT) and Adjuvant Therapies. Preprints. https://doi.org/10.20944/preprints202407.0894.v1
Chicago/Turabian Style
Yoo, J., Jong-Eun Jun and Sang-Yoon Lee. 2024 "Preservation of Vocal Function in Amyotrophic Lateral Sclerosis (ALS) Patients Following Percutaneous Dilatational Tracheostomy (PDT) and Adjuvant Therapies" Preprints. https://doi.org/10.20944/preprints202407.0894.v1
Abstract
To evaluate the efficacy of percutaneous dilatational tracheostomy (PDT) combined with adjuvant therapies in preserving vocal function in amyotrophic lateral sclerosis (ALS) patients. Methods: We performed a retrospective analysis of 47 ALS patients who underwent PDT at the Rodem Hospital from 2021 to 2023. Post-operatively, these patients were provided with a comprehensive treatment plan that included regenerative injection therapy, low-frequency electrical stimulation, respiratory rehabilitation, and swallowing rehabilitation therapy. Additionally, a balloon reduction program was implemented for effective Tracheostomy tube (T-tube) management. The preservation of vocal functions was evaluated 4 weeks following the procedure. Results: While some patients maintained or slightly improved their ALSFRS-R speech scores, the overall trend indicated a de-crease in speech scores post-PDT. This suggests that PDT combined with adjuvant therapies may not universally improve vocal function, but can help maintain it in certain cases. Conclusion: Our findings indicate that PDT combined with mesotherapy, low-frequency electrical stimulation, and swallowing rehabilitation therapy may play a role in maintaining vocal function in limb type ALS patients, though further research is needed to optimize patient management and validate these results.
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
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