Version 1
: Received: 12 July 2024 / Approved: 12 July 2024 / Online: 14 July 2024 (03:11:44 CEST)
How to cite:
Özcan, P.; Düzgün, Ö. The Importance of Preoperative NLR, PLR, and MPV Values in Predicting the Risk of Complications in Colorectal Peritoneal Carcinomatosis. Preprints2024, 2024071091. https://doi.org/10.20944/preprints202407.1091.v1
Özcan, P.; Düzgün, Ö. The Importance of Preoperative NLR, PLR, and MPV Values in Predicting the Risk of Complications in Colorectal Peritoneal Carcinomatosis. Preprints 2024, 2024071091. https://doi.org/10.20944/preprints202407.1091.v1
Özcan, P.; Düzgün, Ö. The Importance of Preoperative NLR, PLR, and MPV Values in Predicting the Risk of Complications in Colorectal Peritoneal Carcinomatosis. Preprints2024, 2024071091. https://doi.org/10.20944/preprints202407.1091.v1
APA Style
Özcan, P., & Düzgün, Ö. (2024). The Importance of Preoperative NLR, PLR, and MPV Values in Predicting the Risk of Complications in Colorectal Peritoneal Carcinomatosis. Preprints. https://doi.org/10.20944/preprints202407.1091.v1
Chicago/Turabian Style
Özcan, P. and Özgül Düzgün. 2024 "The Importance of Preoperative NLR, PLR, and MPV Values in Predicting the Risk of Complications in Colorectal Peritoneal Carcinomatosis" Preprints. https://doi.org/10.20944/preprints202407.1091.v1
Abstract
The Importance of Preoperative NLR, PLR, and MPV Values in Predicting the Risk of Complications in Colorectal Peritoneal Carcinomatosis
Background
Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) measurements can be easily assessed in most hospital laboratories. Our aim is to emphasize the importance of preoperative inflammatory parameters such as NLR, PLR, and MPV in predicting postoperative complications in patients undergoing surgery for colorectal peritoneal carcinomatosis (CRC PC).
Methods
Patients operated for CRC PC were evaluated. Demographic data, NLR, PLR, and MPV values were calculated using the following formulas: NLR = (absolute neutrophil count)/(total lymphocyte count), PLR = (total lymphocyte count)/(total platelet count) × 100, MPV = mean platelet volume calculated by dividing platelet crit (PCT) by total platelet count.
Results
A total of 196 patients with CRC PC were included in the study. A statistically significant relationship was observed between NLR, PLR, MPV, and OS. Patients with an NLR value of 3.77 had a median OS of 22.1 months, whereas those with an NLR value below 3.77 had a median OS of 58.3 months (HR 2.7, 95% CI 1.1–5.3, p
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
