Preprint Review Version 1 This version is not peer-reviewed

The Genomic Variation in Textured Hair: Implications in Developing a Holistic Hair Care Routine

Version 1 : Received: 12 July 2024 / Approved: 15 July 2024 / Online: 15 July 2024 (15:05:40 CEST)

How to cite: Idowu, O. C.; Markiewicz, E.; Oladele, D. The Genomic Variation in Textured Hair: Implications in Developing a Holistic Hair Care Routine. Preprints 2024, 2024071218. https://doi.org/10.20944/preprints202407.1218.v1 Idowu, O. C.; Markiewicz, E.; Oladele, D. The Genomic Variation in Textured Hair: Implications in Developing a Holistic Hair Care Routine. Preprints 2024, 2024071218. https://doi.org/10.20944/preprints202407.1218.v1

Abstract

Human hair is characterised by significant variability, determined by genetic and macromolecular factors. Whilst European hair type has been a focus of extensive research, Afro-textured hair care faces challenges created by insufficient knowledge of its unique properties. Applications of hair care products that are incompatible with Afro-textured hair frequently have detrimental effects on the scalp, including alopecia. This highlights the need for scientific and clinical partnerships to bridge the gap between research and hair care practices and address challenges related to Afro-textured hair. In this review, we performed data mining of the existing literature and in-silico network analysis of the biomarkers relevant to Afro-textured hair. The approaches to hair maintenance are highlighted in the context of hair anatomy and growth cycles, organisation of keratins, surface lipids and chemical bonds. We discuss a range of biomarkers affecting hair fibre's shape and mechanical strength, with the gene interactive network pointing to the hierarchical organisation of important traits, notably hair shaft diameter, keratinisation, hair follicle development and patterning. We propose a better understanding of the genetic traits, molecular structure and biomechanics of Afro-textured hair is required to initiate more effective hair care solutions that would benefit the wider population.

Keywords

textured hair; black skin; gene interactive network; personalised skincare

Subject

Biology and Life Sciences, Life Sciences

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.