Preprint Article Version 1 This version is not peer-reviewed

The Relationship between Maternal Smoking and Infant Birth Weight: Improving Accuracy through Urine Cotinine Analysis and Effective Medical Record Strategies

Version 1 : Received: 22 July 2024 / Approved: 22 July 2024 / Online: 22 July 2024 (19:09:02 CEST)

How to cite: Vojisavljevic, D.; Rudd, D.; Smith, R.; Kandasamy, Y. The Relationship between Maternal Smoking and Infant Birth Weight: Improving Accuracy through Urine Cotinine Analysis and Effective Medical Record Strategies. Preprints 2024, 2024071725. https://doi.org/10.20944/preprints202407.1725.v1 Vojisavljevic, D.; Rudd, D.; Smith, R.; Kandasamy, Y. The Relationship between Maternal Smoking and Infant Birth Weight: Improving Accuracy through Urine Cotinine Analysis and Effective Medical Record Strategies. Preprints 2024, 2024071725. https://doi.org/10.20944/preprints202407.1725.v1

Abstract

We conducted a study to determine if antenatally collected maternal urine cotinine (a metabolite of nicotine) measurements can be used to assess the neonatal impact of nicotine exposure during pregnancy. This was a prospective longitudinal cohort of mother-infant dyads. Only term singleton pregnancies were included. The primary outcome measure was the correlation between maternal urine cotinine and infant birth weight. We analysed data from 238 mother-neonates' dyads. Urine cotinine was detected in 50.4 % (120/238) women from the whole cohort, but only 16% (38/238) self-reported as smokers (chi-square 39.7, p

Keywords

cotinine; birth weight; sex; pregnancy; nicotine

Subject

Medicine and Pharmacology, Pediatrics, Perinatology and Child Health

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