PreprintArticleVersion 1This version is not peer-reviewed
3 Months Follow Up of the Post-COVID Syndrome after Admission in a Specialised Post-COVID Centre – A Prospective Study Focusing Mental Health with Patient Reported Outcome Measures (PROMs)
Version 1
: Received: 23 July 2024 / Approved: 24 July 2024 / Online: 24 July 2024 (08:13:55 CEST)
How to cite:
Schäfer, I. C.; Krehbiel, J.; Adler, W.; Borho, A.; Herold, R.; Greiner, B.; Reuner, M.; Morawa, E.; Erim, Y. 3 Months Follow Up of the Post-COVID Syndrome after Admission in a Specialised Post-COVID Centre – A Prospective Study Focusing Mental Health with Patient Reported Outcome Measures (PROMs). Preprints2024, 2024071903. https://doi.org/10.20944/preprints202407.1903.v1
Schäfer, I. C.; Krehbiel, J.; Adler, W.; Borho, A.; Herold, R.; Greiner, B.; Reuner, M.; Morawa, E.; Erim, Y. 3 Months Follow Up of the Post-COVID Syndrome after Admission in a Specialised Post-COVID Centre – A Prospective Study Focusing Mental Health with Patient Reported Outcome Measures (PROMs). Preprints 2024, 2024071903. https://doi.org/10.20944/preprints202407.1903.v1
Schäfer, I. C.; Krehbiel, J.; Adler, W.; Borho, A.; Herold, R.; Greiner, B.; Reuner, M.; Morawa, E.; Erim, Y. 3 Months Follow Up of the Post-COVID Syndrome after Admission in a Specialised Post-COVID Centre – A Prospective Study Focusing Mental Health with Patient Reported Outcome Measures (PROMs). Preprints2024, 2024071903. https://doi.org/10.20944/preprints202407.1903.v1
APA Style
Schäfer, I. C., Krehbiel, J., Adler, W., Borho, A., Herold, R., Greiner, B., Reuner, M., Morawa, E., & Erim, Y. (2024). 3 Months Follow Up of the Post-COVID Syndrome after Admission in a Specialised Post-COVID Centre – A Prospective Study Focusing Mental Health with Patient Reported Outcome Measures (PROMs). Preprints. https://doi.org/10.20944/preprints202407.1903.v1
Chicago/Turabian Style
Schäfer, I. C., Eva Morawa and Yesim Erim. 2024 "3 Months Follow Up of the Post-COVID Syndrome after Admission in a Specialised Post-COVID Centre – A Prospective Study Focusing Mental Health with Patient Reported Outcome Measures (PROMs)" Preprints. https://doi.org/10.20944/preprints202407.1903.v1
Abstract
Background and objective: The impairments and duration of PASC (Post-acute sequelae of COVID-19) symptoms in mental health have up to date not been comprehensively examined. Our objective is to provide longitudinal data on the mental health of Post-COVID patients and to identify risk and protective factors associated with a severe or prolonged course.
Methods: Mental health of 265 Post-COVID patients of the outpatient Post-COVID centre of the University-Hospital Erlangen was assessed 17.1 (T0) and 22.5 months after infection (T1). An online survey with validated questionnaires for Post-COVID symptoms (Post-COVID-Syndrome-Score), depression (Patient-Health-Questionnaire 9), somatic symptoms (Patient-Health-Questionnaire 15), anxiety (Generalized-Anxiety-Disorder 7), fatigue (Fatigue-Severity-Scale) and Post-Exertional Malaise (PEM) (DePaul Post-Exertional-Malaise Screening) was conducted in the home environment.
Results: 80% of patients experienced severe PASC at follow up. Clinically relevant symptoms of depression, persistent somatic symptoms, anxiety, and fatigue were reported by 55.8%, 72.5%, 18.9% and 89.4% respectively. Depressive, anxiety and somatic symptom severity decreased significantly over time; fatigue and PEM remained on an unchanged high level. Risk factor for higher depression scores was older age; prior psychiatric illness treated with psychotherapy was associated with more severe depressive, somatic, anxiety and PASC symptoms. PEM symptoms were significantly associated with longer duration between acute infection and initial presentation in the Post-COVID centre.
Conclusion: Our findings align with previous research, claiming severe mental health symptoms in PASC syndrome, lasting for months after infection. In-depth assessment of risk and protective factors for mental health implications of PASC is needed for planning health services and disease prevention.
Medicine and Pharmacology, Psychiatry and Mental Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
