Preprint Review Version 1 This version is not peer-reviewed

The Role of Omega-3 Polyunsaturated Fatty Acids in Muscle Growth and Recovery: Implications for Aging and Performance

Version 1 : Received: 29 July 2024 / Approved: 30 July 2024 / Online: 30 July 2024 (07:40:18 CEST)

How to cite: Varamini, B.; Yang, J. O.; Merry, B. J.; Dau, D. J. The Role of Omega-3 Polyunsaturated Fatty Acids in Muscle Growth and Recovery: Implications for Aging and Performance. Preprints 2024, 2024072418. https://doi.org/10.20944/preprints202407.2418.v1 Varamini, B.; Yang, J. O.; Merry, B. J.; Dau, D. J. The Role of Omega-3 Polyunsaturated Fatty Acids in Muscle Growth and Recovery: Implications for Aging and Performance. Preprints 2024, 2024072418. https://doi.org/10.20944/preprints202407.2418.v1

Abstract

Omega-3 polyunsaturated fatty acids (PUFAs) play a critical yet underappreciated role in muscle health, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Through a review of current literature, we analyze the effects of these nutrients on muscle protein synthesis, mass, strength, and recovery. Studies demonstrate that omega-3 PUFAs enhance muscle protein synthesis via the mTOR pathway and possess anti-inflammatory properties that may reduce muscle damage and atrophy, particularly in older adults. Their potential to improve muscle function and mitigate exercise-induced damage is also reviewed, highlighting relevance for athletes and active individuals. Further research on optimal dosages and long-term effects of omega-3 supplementation is needed, providing a basis for future studies and practical recommendations for leveraging these nutrients to support muscle health.

Keywords

omega-3; muscle; growth; recovery; performance; EPA; DHA.

Subject

Biology and Life Sciences, Other

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