Preprint Article Version 1 This version is not peer-reviewed

Perioperative and Long Term Outcomes of Acute Stanford Type A Aortic Dissection Repair in Octogenarians

Version 1 : Received: 4 August 2024 / Approved: 5 August 2024 / Online: 5 August 2024 (08:26:17 CEST)

How to cite: Masraf, H.; Navaratnarajah, M.; Viola, L.; Sef, D.; Malvindi, P. G.; Miskolczi, S.; Velisaaris, T.; Luthra, S. Perioperative and Long Term Outcomes of Acute Stanford Type A Aortic Dissection Repair in Octogenarians. Preprints 2024, 2024080258. https://doi.org/10.20944/preprints202408.0258.v1 Masraf, H.; Navaratnarajah, M.; Viola, L.; Sef, D.; Malvindi, P. G.; Miskolczi, S.; Velisaaris, T.; Luthra, S. Perioperative and Long Term Outcomes of Acute Stanford Type A Aortic Dissection Repair in Octogenarians. Preprints 2024, 2024080258. https://doi.org/10.20944/preprints202408.0258.v1

Abstract

Background The aims of this study were to assess the peri-operative morbidity, mortality and long-term survival of octogenarians undergoing ATAAD repair, and to compare open and closed distal anastomosis techniques. Methods This was a single-centre retrospective study (2007-2021). Open versus closed distal anastomosis were compared. Uni and multi-variable logistic regression analyses were performed to identify independent predictors of in-hospital mortality. Kaplan-Meier and Cox proportional hazards methods were used to compare long-term survival. Results Fifty octogenarians patients were included (median age - 82 years, closed distal – 22, open distal - 28). Median CPB time was 187 minutes (open distal vs closed distal group; 219 minutes vs 115.5 minutes, p30 days or return to theatre; HR; 4.1, p=0.02) predicted adverse survival. Open distal anastomosis did no impact survival. Conclusions – ATAAD repair in selected octogenarians has favourable short and long-term survival. There is no significant difference between open versus closed distal anastomosis strategies.

Keywords

acute aortic dissection; octogenarians; type A aortic dissection; perioperative outcomes

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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