Version 1
: Received: 5 August 2024 / Approved: 5 August 2024 / Online: 6 August 2024 (08:37:13 CEST)
How to cite:
Kirsch, S.; Marik, P.; Rogers, C.; Cosgrove, K.; Mead, M. N. A Novel Practical Approach for Directly Assessing COVID-19 Vaccine Efficacy against Hospitalization. Preprints2024, 2024080338. https://doi.org/10.20944/preprints202408.0338.v1
Kirsch, S.; Marik, P.; Rogers, C.; Cosgrove, K.; Mead, M. N. A Novel Practical Approach for Directly Assessing COVID-19 Vaccine Efficacy against Hospitalization. Preprints 2024, 2024080338. https://doi.org/10.20944/preprints202408.0338.v1
Kirsch, S.; Marik, P.; Rogers, C.; Cosgrove, K.; Mead, M. N. A Novel Practical Approach for Directly Assessing COVID-19 Vaccine Efficacy against Hospitalization. Preprints2024, 2024080338. https://doi.org/10.20944/preprints202408.0338.v1
APA Style
Kirsch, S., Marik, P., Rogers, C., Cosgrove, K., & Mead, M. N. (2024). A Novel Practical Approach for Directly Assessing COVID-19 Vaccine Efficacy against Hospitalization. Preprints. https://doi.org/10.20944/preprints202408.0338.v1
Chicago/Turabian Style
Kirsch, S., Kirstin Cosgrove and M. Nathaniel Mead. 2024 "A Novel Practical Approach for Directly Assessing COVID-19 Vaccine Efficacy against Hospitalization" Preprints. https://doi.org/10.20944/preprints202408.0338.v1
Abstract
We revisit a 2023 JAMA-published analysis of data from patients admitted for either COVID-19 or influenza to U.S. Veterans Administration (VA) hospitals in the fall/winter of 2022-2023. We note that baseline characteristics between the cohorts were similar, and the difference in vaccination rates was minimal, even after propensity score weighting. Had the vaccines been even minimally effective, significant differences in vaccination percentages would be expected. These findings call into question any efficacy claims associated with either the COVID-19 or influenza vaccines. Furthermore, the lack of efficacy of the influenza vaccines in reducing hospitalization is consistent with an earlier detailed study that found the same lack of efficacy, further validating the current result. This suggests that comparing vaccination rates between those hospitalized for different vaccine-preventable diseases can serve as a practical method for validating the vaccine efficacy claims of different vaccines.
Medicine and Pharmacology, Epidemiology and Infectious Diseases
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
