Preprint Article Version 1 This version is not peer-reviewed

Propensity-Matched Comparison of Percutaneous Versus Surgical Access for Transfemoral Transcatheter Aortic Valve Replacement (TAVR)

Version 1 : Received: 5 August 2024 / Approved: 6 August 2024 / Online: 8 August 2024 (04:17:35 CEST)

How to cite: Papadopoulos, G. E.; Ninios, I.; Leptopoulos, E.; Papazoglou, K.; Konstantinidis, K.; Evangelou, S.; Ioannidis, A.; Ninios, V. Propensity-Matched Comparison of Percutaneous Versus Surgical Access for Transfemoral Transcatheter Aortic Valve Replacement (TAVR). Preprints 2024, 2024080452. https://doi.org/10.20944/preprints202408.0452.v1 Papadopoulos, G. E.; Ninios, I.; Leptopoulos, E.; Papazoglou, K.; Konstantinidis, K.; Evangelou, S.; Ioannidis, A.; Ninios, V. Propensity-Matched Comparison of Percutaneous Versus Surgical Access for Transfemoral Transcatheter Aortic Valve Replacement (TAVR). Preprints 2024, 2024080452. https://doi.org/10.20944/preprints202408.0452.v1

Abstract

Background: Transcatheter aortic valve replacement (TAVR) is a proven treatment for severe aortic stenosis (AS). Transfemoral access is the most prevalent method, achieved either surgically or percutaneously. This study compares in-hospital outcomes and length of stay between surgical cut-down and fully percutaneous approaches. Methods: This retrospective, propensity-matched study analyzed medical records of all patients who underwent transfemoral TAVR at our center from January 2019 to December 2023. Outcomes were assessed based on Valve Academic Research Consortium-2 (VARC-2) consensus criteria. Results: 251 TAVR patients (77 propensity score matching pairs) were included (55% female) with a median (IQR) age of 80 (11) years. Surgical cut-down showed fewer vascular complications, bleeding, and transfusions. No death, stroke, atrial fibrillation (AF), or need for pacemaker was reported in this group. Fewer mean hospitali-zation days were observed in the total cohort over the years (p< 0.001). This reduction was more pronounced after 2021 when the surgical approach was adopted. Mean hospitalization days were 6.40 ±6.46 for percutaneous and 4.34 ±1.61 for surgical groups (p< 0.001). Conclusions: Surgical cut-down for TAVR femoral access yields superior outcomes and shorter hospital stays compared to fully percutaneous methods.

Keywords

transcatheter aortic valve replacement; femoral access; surgical cut-down; percutaneous; in-hospital outcomes; hospital length of stay

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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