Preprint Article Version 1 This version is not peer-reviewed

The Relationship between Vitamin D Levels, Insulin Resistance and Monocyte to HDL- -Cholesterol Ratio in Children

Version 1 : Received: 13 August 2024 / Approved: 14 August 2024 / Online: 14 August 2024 (18:04:09 CEST)

How to cite: Okuyan, O.; Dumur, S.; Elgormus, N.; Uzun, H. The Relationship between Vitamin D Levels, Insulin Resistance and Monocyte to HDL- -Cholesterol Ratio in Children. Preprints 2024, 2024081041. https://doi.org/10.20944/preprints202408.1041.v1 Okuyan, O.; Dumur, S.; Elgormus, N.; Uzun, H. The Relationship between Vitamin D Levels, Insulin Resistance and Monocyte to HDL- -Cholesterol Ratio in Children. Preprints 2024, 2024081041. https://doi.org/10.20944/preprints202408.1041.v1

Abstract

Objective: In this study, we investigated vitamin D, inflammatory hematologic ratios such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), MHR and plasma atherogenic index (PAI) and possible relationships with insulin resistance in children. Methods: A total of 210 individuals, including 96 children with insulin resistance and 114 children without insulin resistance, aged 6-18 years, who were admitted to the Pediatric Endocrinology Outpatient Clinic at Medicine Hospital, Istanbul Atlas University were included in our study. Result: NLR, PLR, SII and MHR were significantly higher in patients with insulin resistance compared to those without. Fasting insulin, PAI, HOMA-IR, HOMA- were significantly higher and QUICKI was significantly lower in patients with insulin resistance compared to those without insulin resistance. NLR, SII and MHR were lower in normal vitamin D groups than the others were (p

Keywords

Children; vitamin D; insulin resistance; monocyte/HDL ratio; inflammatory index

Subject

Medicine and Pharmacology, Clinical Medicine

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.