Version 1
: Received: 15 August 2024 / Approved: 16 August 2024 / Online: 19 August 2024 (03:33:37 CEST)
How to cite:
Niedźwiedź, M.; Skibińska, M.; Ciążyńska, M.; Noweta, M.; Czerwińska, A.; Krzyścin, J.; Narbutt, J.; Lesiak, A. Seasonality of Psoriasis: From Genes to the Clinical Phenomena. Preprints2024, 2024081222. https://doi.org/10.20944/preprints202408.1222.v1
Niedźwiedź, M.; Skibińska, M.; Ciążyńska, M.; Noweta, M.; Czerwińska, A.; Krzyścin, J.; Narbutt, J.; Lesiak, A. Seasonality of Psoriasis: From Genes to the Clinical Phenomena. Preprints 2024, 2024081222. https://doi.org/10.20944/preprints202408.1222.v1
Niedźwiedź, M.; Skibińska, M.; Ciążyńska, M.; Noweta, M.; Czerwińska, A.; Krzyścin, J.; Narbutt, J.; Lesiak, A. Seasonality of Psoriasis: From Genes to the Clinical Phenomena. Preprints2024, 2024081222. https://doi.org/10.20944/preprints202408.1222.v1
APA Style
Niedźwiedź, M., Skibińska, M., Ciążyńska, M., Noweta, M., Czerwińska, A., Krzyścin, J., Narbutt, J., & Lesiak, A. (2024). Seasonality of Psoriasis: From Genes to the Clinical Phenomena. Preprints. https://doi.org/10.20944/preprints202408.1222.v1
Chicago/Turabian Style
Niedźwiedź, M., Joanna Narbutt and Aleksandra Lesiak. 2024 "Seasonality of Psoriasis: From Genes to the Clinical Phenomena" Preprints. https://doi.org/10.20944/preprints202408.1222.v1
Abstract
Psoriasis is a multifactorial, chronic, and inflammatory disease that severely impacts patients’ quality of life. The disease is caused by genetic irregularities affected by the epigenetic and environmental factors. Some of these factors may include the seasonal changes, such as solar radiation, air pollution and humidity, and changes in circadian rhythm, especially in the temporal and polar zones. Thus, some psoriasis patients report seasonal variability of symptoms. Through a comprehensive review, we aim to delve deeper into the intricate interplay between seasonality, environmental factors, and the genetic and epigenetic landscape of psoriasis. By elucidating these complex relationships, we strive to provide insights that may inform targeted interventions and personalized management strategies for individuals living with psoriasis.
Keywords
psoriasis; environmental factors; genetics; epigenetics; solar radiation; humidity; air pollution; circadian rhythm; geoepidemiology; seasonality
Subject
Medicine and Pharmacology, Dermatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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