Preprint Article Version 1 This version is not peer-reviewed

Prevalence, Management, and Outcomes of Atrial Fibrillation in Paediatric Patients: Insights from a Tertiary Cardiology Centre

Version 1 : Received: 17 August 2024 / Approved: 18 August 2024 / Online: 20 August 2024 (05:13:11 CEST)

How to cite: Constante, A. D.; Suarez, J.; Lourenço, G.; Portugal, G.; Cunha, P. S.; Oliveira, M. M.; Trigo, C.; Pinto, F. F.; Laranjo, S. Prevalence, Management, and Outcomes of Atrial Fibrillation in Paediatric Patients: Insights from a Tertiary Cardiology Centre. Preprints 2024, 2024081276. https://doi.org/10.20944/preprints202408.1276.v1 Constante, A. D.; Suarez, J.; Lourenço, G.; Portugal, G.; Cunha, P. S.; Oliveira, M. M.; Trigo, C.; Pinto, F. F.; Laranjo, S. Prevalence, Management, and Outcomes of Atrial Fibrillation in Paediatric Patients: Insights from a Tertiary Cardiology Centre. Preprints 2024, 2024081276. https://doi.org/10.20944/preprints202408.1276.v1

Abstract

Background: Atrial fibrillation (AF) is increasingly recognised in paediatric patients and presents unique management challenges. We aimed to investigate the prevalence, management strategies, and outcomes of AF in this population. Methods: This retrospective analysis was conducted at a tertiary paediatric cardiology centre, including patients aged ≤18 years who were diagnosed with AF between January 2015 and December 2023. Demographic details, clinical manifestations, treatments, and outcomes were also analysed. Patients with documented AF episodes were in-cluded. Descriptive statistics were used to assess the treatment efficacy, recurrence, and complications. Results: The study included 36 patients (mean age, 15 years; 58% male). Of these, 52.8% had acquired heart disease, 16.7% had congenital anomalies, and 16.7% had lone AF. The initial treatment involved electrical cardioversion (53.3%) and pharmacological conversion with amiodarone (46.7%). Over 80% of the patients received rhythm control therapy, and 63.9% were placed on oral anticoagulation, primarily for rheumatic and congenital heart diseases. The success rate of rhythm control was 50% with an AF recurrence rate of 3.8%. Ischaemic stroke was the most common complication (n=3) occurring in patients with underlying heart disease. Conclusion: AF in paediatric patients is predominantly associated with rheumatic and congenital heart diseases, although a notable proportion of patients present with lone AF. Despite the high intervention and antiarrhythmic therapy rates, neurological complications, particularly in those with underlying heart disease, remain a significant concern. These findings highlight the need for further com-prehensive studies to understand better the aetiology, risk factors, and management of paediatric AF.

Keywords

Atrial fibrillation; paediatric arrhythmias; paediatric cardiology; congenital heart disease; rheumatic heart disease

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.